Andres D Klein
Overview
Explore the profile of Andres D Klein including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
656
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Contreras P, Tapia P, Gonzalez-Hodar L, Peluso I, Soldati C, Napolitano G, et al.
iScience
. 2020 Nov;
23(11):101691.
PMID: 33163944
The transcription factor EB (TFEB) has emerged as a master regulator of lysosomal biogenesis, exocytosis, and autophagy, promoting the clearance of substrates stored in cells. c-Abl is a tyrosine kinase...
12.
Vial C, Calderon J, Klein A
Curr Mol Med
. 2020 Jul;
21(1):2-4.
PMID: 32660402
The COVID-19 plague is hitting mankind. Several viruses, including SARS-CoV-1, MERS-CoV, EBOV, and SARS-CoV-2, use the endocytic machinery to enter the cell. Genomic variants in NPC1, which encodes for the...
13.
Klein A, Gonzalez de la Vega J, Zanlungo S
Int J Mol Sci
. 2020 Apr;
21(6).
PMID: 32244854
Niemann-Pick type C (NPC), a lysosomal storage disorder, is mainly caused by mutations in the gene. Niemann-Pick type C patients and mice show intracellular cholesterol accumulation leading to hepatic failure...
14.
Encina G, Castillo-Laborde C, Lecaros J, Dubois-Camacho K, Calderon J, Aguilera X, et al.
Orphanet J Rare Dis
. 2020 Jan;
14(1):289.
PMID: 31931841
Rare diseases (RDs) are a large number of diverse conditions with low individual prevalence, but collectively may affect up to 3.5-5.9% of the population. They have psychosocial and economic impact...
15.
Olivares G, Olguin P, Klein A
Trends Mol Med
. 2019 Nov;
25(12):1052-1055.
PMID: 31676188
A mechanistic understanding of the diverse clinical manifestations of Parkinson's disease (PD) and variable patient response to treatments is lacking. Genetically diverse PD model organisms can be used to map...
16.
Gutierrez J, Gomez I, Chiarello D, Salsoso R, Klein A, Guzman-Gutierrez E, et al.
Biochim Biophys Acta Mol Basis Dis
. 2019 Apr;
1866(2):165448.
PMID: 30954558
Preeclampsia is a syndrome characterised by vascular dysfunction, impaired angiogenesis, and hypertension during pregnancy. Even when the precise pathophysiology of preeclampsia remains elusive, impaired vascular remodelling and placental angiogenesis in...
17.
Klein A, Oyarzun J, Cortez C, Zanlungo S
Int J Mol Sci
. 2018 Nov;
19(11).
PMID: 30441844
Niemann⁻Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the or genes. Soon after birth, some patients present with...
18.
Calderon J, Klein A
Mol Genet Metab Rep
. 2018 Jul;
15:135-136.
PMID: 30023307
No abstract available.
19.
Klein A, Mazzulli J
Brain
. 2018 Jun;
141(8):2255-2262.
PMID: 29860491
Common forms of Parkinson's disease have long been described as idiopathic, with no single penetrant genetic factor capable of influencing disease aetiology. Recent genetic studies indicate a clear association of...
20.
Klein A
Physiol Genomics
. 2017 Jan;
49(3):177-179.
PMID: 28130429
The genetic basis of the phenotypic variability observed in patients can be studied in mice by generating disease models through genetic or chemical interventions in many genetic backgrounds where the...