Andreia Machado Leopoldino
Overview
Explore the profile of Andreia Machado Leopoldino including associated specialties, affiliations and a list of published articles.
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41
Citations
284
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Recent Articles
1.
Chagas P, Garcia C, Chagas H, Yeudall W, Yu J, Baban B, et al.
Mol Biol Rep
. 2025 Feb;
52(1):220.
PMID: 39934454
Background: Oral cancer is the most common malignancy of the oral cavity and facial region, affecting the mucosal and epithelial surfaces in the mouth and lips. Unfortunately, OC is often...
2.
Chagas P, Garcia C, Sousa L, da Silva G, de Sousa G, Marcelino R, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39595926
Emerging evidence suggests that aberrant expression levels of Sigma1 (, also known as sigma-1 receptor) have been implicated in the progression of various diseases, including cancer. However, its significance in...
3.
Milan T, da Silva G, Silva G, Sousa L, Leopoldino A
Am J Pathol
. 2024 Oct;
195(2):321-333.
PMID: 39476954
Alterations in miRNAs, p53, and sphingolipid metabolism are associated with head and neck squamous cell carcinoma (HNSCC). However, the role of sphingosine kinase (SK)-2, an enzyme crucial for sphingolipid metabolism,...
4.
da Silva G, Milan T, Chagas P, Trevisan G, Ferraz C, Leopoldino A
Epigenomics
. 2023 Dec;
16(4):249-257.
PMID: 38131159
The SET gene has four transcripts reported in NCBI, coding two isoforms of SET proteins. The most known function of SET protein is inhibiting protein phosphatase 2A, a tumor suppressor,...
5.
da Silva G, Milan T, Leopoldino A
Gene
. 2023 Dec;
897:148063.
PMID: 38048970
There is a known correlation between cancer and changes in sphingolipids, specifically the production of sphingosine-1-phosphate (S1P) by sphingosine kinases 1 and 2 (SPHK1/SPHK2). However, a potential relationship between bioactive...
6.
Torres L, Silva G, Alves J, Ushida T, Potenza J, Garcia C, et al.
J Oral Pathol Med
. 2023 Nov;
53(1):42-52.
PMID: 37946676
Background: Oral squamous cell carcinoma has high recurrence and cisplatin resistance. As cancer stem cells, autophagy, and sphingolipids have been appointed as associated with chemotherapy resistance, we tested combined treatments...
7.
Brigliadori Fugio L, Silva G, Ferraz C, Trevisan G, Coeli-Lacchini F, Garcia C, et al.
Biochim Biophys Acta Mol Cell Res
. 2023 Oct;
1871(1):119616.
PMID: 37898377
Sphingosine-1-phosphate (S1P) signaling has been widely explored as a therapeutic target in cancer. Sphingosine kinase 2 (SK2), one of the kinases that phosphorylate sphingosine, has a cell type and cell...
8.
Pereira T, Ramos D, Sobral L, Martins Y, Petrilli R, Fantini M, et al.
Int J Pharm
. 2023 Sep;
646:123431.
PMID: 37739094
The potential of low-frequency ultrasound (LFU) combined with nanotechnology-based formulations in improving skin tumors topical treatment was investigated. The impact of solid lipid nanoparticles (SLN) and hydrophilic nanogels as coupling...
9.
Silva G, de Arruda J, Almeida T, Oliveira S, Rocha P, Mesquita R, et al.
Exp Mol Pathol
. 2023 Sep;
134:104870.
PMID: 37690528
Bisphenol A (BPA) is an endocrine-disrupting chemical with a potential role in endocrine cancers. However, the effects of BPA on the salivary glands have been barely explored. We investigated the...
10.
do Valle I, Oliveira S, da Silva J, Peterle G, Co A, Sousa-Neto S, et al.
Sci Rep
. 2023 Apr;
13(1):5460.
PMID: 37015965
Pericytes are perivascular cells related to vessel structure and angiogenesis that can interact with neoplastic cells, interfering with cancer progression and outcomes. This study focused on the characterization of pericytes...