Andrei V Tikhonov
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Explore the profile of Andrei V Tikhonov including associated specialties, affiliations and a list of published articles.
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14
Citations
125
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Recent Articles
1.
Pendina A, Krapivin M, Chiryaeva O, Petrova L, Pashkova E, Golubeva A, et al.
Cells
. 2025 Jan;
14(1.
PMID: 39791709
Chromosomal abnormalities of the embryo are the most common cause of first-trimester pregnancy loss. In this single-center study, we assessed the frequency and the spectrum of chromosomal abnormalities in miscarriages...
2.
Tikhonov A, Krapivin M, Malysheva O, Komarova E, Golubeva A, Efimova O, et al.
J Clin Med
. 2024 Jun;
13(11).
PMID: 38893001
In recent years, preimplantation genetic testing for aneuploidies (PGT-A) has become widespread in assisted reproduction. However, contrary to expectations, PGT-A does not significantly improve the clinical outcomes of assisted reproductive...
3.
Pendina A, Krapivin M, Sagurova Y, Mekina I, Komarova E, Tikhonov A, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445605
Predicting the clinical outcomes of intracytoplasmic sperm injection (ICSI) cycles that use the testicular spermatozoa of azoospermic patients presents a challenge. Thus, the development of additional approaches to assessing the...
4.
Talantova O, Koltsova A, Tikhonov A, Pendina A, Malysheva O, Tarasenko O, et al.
Genes (Basel)
. 2023 Apr;
14(4).
PMID: 37107671
We report on the case of prenatal detection of trisomy 2 in placental biopsy and further algorithm of genetic counseling and testing. A 29-year-old woman with first-trimester biochemical markers refused...
5.
Krapivin M, Tikhonov A, Efimova O, Pendina A, Smirnova A, Chiryaeva O, et al.
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34205622
The present study investigates telomere length (TL) in dividing chorionic cytotrophoblast cells from karyotypically normal and abnormal first trimester miscarriages and ongoing pregnancies. Using Q-FISH, we measured relative TLs in...
6.
Pendina A, Krapivin M, Efimova O, Tikhonov A, Mekina I, Komarova E, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34070406
The human lifespan is strongly influenced by telomere length (TL) which is defined in a zygote-when two highly specialised haploid cells form a new diploid organism. Although TL is a...
7.
Efimova O, Koltsova A, Krapivin M, Tikhonov A, Pendina A
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32370155
Convincing evidence accumulated over the last decades demonstrates the crucial role of epigenetic modifications for mammalian genome regulation and its flexibility. DNA methylation and demethylation is a key mechanism of...
8.
Reproductive History of a Woman With 8p and 18p Genetic Imbalance and Minor Phenotypic Abnormalities
Pendina A, Shilenkova Y, Talantova O, Efimova O, Chiryaeva O, Malysheva O, et al.
Front Genet
. 2019 Dec;
10:1164.
PMID: 31824569
We report on the phenotype and the reproductive history of an adult female patient with an unbalanced karyotype: 8p23 and 18p11.3 terminal deletions and 8p22 duplication. The indication for karyotyping...
9.
Efimova O, Pendina A, Krapivin M, Kopat V, Tikhonov A, Petrovskaia-Kaminskaia A, et al.
Cytogenet Genome Res
. 2018 Nov;
156(3):150-157.
PMID: 30497063
5-hydroxymethylcytosine (5hmC) is an oxidative derivative of 5-methylcytosine (5mC). Recent studies have revealed a sharp difference in the levels of 5hmC in 2 opposite DNA strands of a given chromosome...
10.
Pendina A, Efimova O, Krapivin M, Mekina I, Tikhonov A, Koltsova A, et al.
Mol Reprod Dev
. 2018 Oct;
85(12):893-895.
PMID: 30320470
No abstract available.