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Andrei Golosov

Explore the profile of Andrei Golosov including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Salcius M, Tutter A, Fouche M, Koc H, King D, Dhembi A, et al.
RSC Chem Biol . 2025 Mar; PMID: 40059881
Many disease-relevant and functionally well-validated targets are difficult to drug. Their poorly defined 3D structure without deep hydrophobic pockets makes the development of ligands with low molecular weight and high...
2.
Pearlstein R, McKay D, Hornak V, Dickson C, Golosov A, Harrison T, et al.
Curr Top Med Chem . 2017 Apr; 17(23):2642-2662. PMID: 28413952
Cellular drug targets exist within networked function-generating systems whose constituent molecular species undergo dynamic interdependent non-equilibrium state transitions in response to specific perturbations (i.e.. inputs). Cellular phenotypic behaviors are manifested...