Andreas Wittgens
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Explore the profile of Andreas Wittgens including associated specialties, affiliations and a list of published articles.
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14
Citations
329
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Recent Articles
1.
Widberger J, Wittgens A, Klaunig S, Kramer M, Kissmann A, Hofele F, et al.
Microorganisms
. 2024 Mar;
12(3).
PMID: 38543580
The establishment of sustainable processes for the production of commodity chemicals is one of today's central challenges for biotechnological industries. The chemo-autotrophic fixation of CO and the subsequent production of...
2.
Raber H, Sejfijaj J, Kissmann A, Wittgens A, Gonzalez-Garcia M, Alba A, et al.
Pathogens
. 2021 Apr;
10(4).
PMID: 33924039
Recently two peptides isolated from the Cuban freshwater snail (Pilsbry, 1927) were described to have antimicrobial activity against bacterial pathogens. Here we show considerable activities of Pom-1 and Pom-2 to...
3.
Wittgens A, Rosenau F
Front Bioeng Biotechnol
. 2020 Nov;
8:594010.
PMID: 33195161
The first heterologous expression of genes responsible for the production of rhamnolipids was already implemented in the mid-1990s during the functional identification of the operon. This was the starting shot...
4.
Kubiczek D, Flaig C, Raber H, Dietz S, Kissmann A, Heerde T, et al.
Macromol Biosci
. 2020 Feb;
20(4):e2000005.
PMID: 32104975
The pathogenic yeast Candida auris has received increasing attention due to its ability to cause fatal infections, its resistance toward important fungicides, and its ability to persist on surfaces including...
5.
Bator I, Wittgens A, Rosenau F, Tiso T, Blank L
Front Bioeng Biotechnol
. 2020 Feb;
7:480.
PMID: 32010683
KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways. The synthetic operons...
6.
Arnold S, Henkel M, Wanger J, Wittgens A, Rosenau F, Hausmann R
AMB Express
. 2019 Jun;
9(1):80.
PMID: 31152276
In many cases in industrial biotechnology, substrate costs make up a major part of the overall production costs. One strategy to achieve more cost-efficient processes in general is to exploit...
7.
Wittgens A, Rosenau F
Appl Microbiol Biotechnol
. 2018 Jul;
102(19):8175-8185.
PMID: 30032436
Rhamnolipids are biosurfactants with an enormous potential to replace or complement classic surfactants in industrial applications. They consist of one or two L-rhamnose residues linked to one or two 3-hydroxyfatty...
8.
Wittgens A, Santiago-Schuebel B, Henkel M, Tiso T, Blank L, Hausmann R, et al.
Appl Microbiol Biotechnol
. 2017 Dec;
102(3):1229-1239.
PMID: 29264775
Rhamnolipids are biosurfactants consisting of rhamnose (Rha) molecules linked through a β-glycosidic bond to 3-hydroxyfatty acids with various chain lengths, and they have an enormous potential for various industrial applications....
9.
Tiso T, Zauter R, Tulke H, Leuchtle B, Li W, Behrens B, et al.
Microb Cell Fact
. 2017 Dec;
16(1):225.
PMID: 29241456
Background: Rhamnolipids are biosurfactants featuring surface-active properties that render them suitable for a broad range of industrial applications. These properties include their emulsification and foaming capacity, critical micelle concentration, and...
10.
Tiso T, Sabelhaus P, Behrens B, Wittgens A, Rosenau F, Hayen H, et al.
Metab Eng Commun
. 2017 Nov;
3:234-244.
PMID: 29142825
Metabolic engineering of microbial cell factories for the production of heterologous secondary metabolites implicitly relies on the intensification of intracellular flux directed toward the product of choice. Apart from reactions...