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Andreas Thieme

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Articles 21
Citations 97
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Recent Articles
1.
Berger M, Garcia-Moreno H, Ferreira M, Hubener-Schmid J, Schaprian T, Wegner P, et al.
medRxiv . 2025 Feb; PMID: 39974031
Background: Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominantly inherited adult-onset disease. We aimed to describe longitudinal changes in clinical and biological findings and to identify predictors for clinical...
2.
Steiner K, Nicksirat S, Thieme A, Muntefering L, Ernst T, Timmann D, et al.
Brain Behav . 2025 Feb; 15(2):e70364. PMID: 39973028
Introduction: Cerebellar brain inhibition (CBI) is a way to quantify the cerebellar influence on the motor cortex in humans. Studies suggest that the orientation of the transcranial magnetic stimulation (TMS)...
3.
Reinehr S, Neuendorff N, Van der Veen R, Langenbach B, Thieme A
BMC Med Educ . 2024 Dec; 24(1):1557. PMID: 39736613
Background: Sexual health is an important aspect of human well-being. In terms of sexual health and healthcare, sex workers might need more specialized care than others, given their higher risk...
4.
Liu Q, Rubarth K, Faber J, Sulzer P, Dogan I, Barkhoff M, et al.
J Neurol . 2024 Dec; 272(1):83. PMID: 39708269
Background: Cognitive and neuropsychiatric impairment, known as cerebellar cognitive affective syndrome (CCAS), may be present in cerebellar disorders. This study identified distinct CCAS subtypes in cerebellar patients using cluster analysis....
5.
Mohren L, Erdlenbruch F, Leitao E, Kilpert F, Hones G, Kaya S, et al.
Nat Commun . 2024 Sep; 15(1):7665. PMID: 39227614
Repeat expansions in FGF14 cause autosomal dominant late-onset cerebellar ataxia (SCA27B) with estimated pathogenic thresholds of 250 (incomplete penetrance) and 300 AAG repeats (full penetrance), but the sequence of pathogenic...
6.
Thieme A, Depienne C, Timmann D
Med Genet . 2024 Jun; 33(4):301-310. PMID: 38835435
The cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) is a late-onset and recessively inherited ataxia. For many years, CANVAS has been diagnosed based on the clinical phenotype. Only recently,...
7.
Schellen S, Zeidan P, Ernst T, Thieme A, Nicksirat S, Merz C, et al.
Front Hum Neurosci . 2024 Jan; 17:1328283. PMID: 38264350
Fear is a vital defense mechanism to potential threats, which is influenced by the cerebellum. While the cerebellum's role in acquiring fear responses is well understood, limited knowledge exists about...
8.
Batsikadze G, Pakusch J, Klein M, Ernst T, Thieme A, Nicksirat S, et al.
eNeuro . 2024 Jan; 11(2). PMID: 38176906
Functional brain imaging studies in humans suggest involvement of the cerebellum in fear conditioning but do not allow conclusions about the functional significance. The main aim of the present study...
9.
Faber J, Berger M, Wilke C, Hubener-Schmid J, Schaprian T, Santana M, et al.
Ann Neurol . 2023 Nov; 95(2):400-406. PMID: 37962377
Spinocerebellar ataxia type 3/Machado-Joseph disease is the most common autosomal dominant ataxia. In view of the development of targeted therapies, knowledge of early biomarker changes is needed. We analyzed cross-sectional...
10.
Rudolph S, Badura A, Lutzu S, Pathak S, Thieme A, Verpeut J, et al.
J Neurosci . 2023 Nov; 43(45):7554-7564. PMID: 37940582
The cerebellum, traditionally associated with motor coordination and balance, also plays a crucial role in various aspects of higher-order function and dysfunction. Emerging research has shed light on the cerebellum's...