Andreas Schonle
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Explore the profile of Andreas Schonle including associated specialties, affiliations and a list of published articles.
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27
Citations
1480
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Recent Articles
1.
Heine J, Wurm C, Keller-Findeisen J, Schonle A, Harke B, Reuss M, et al.
Rev Sci Instrum
. 2018 Jun;
89(5):053701.
PMID: 29864829
Modern fluorescence superresolution microscopes are capable of imaging living cells on the nanometer scale. One of those techniques is stimulated emission depletion (STED) which increases the microscope's resolution many times...
2.
Chmyrov A, Leutenegger M, Grotjohann T, Schonle A, Keller-Findeisen J, Kastrup L, et al.
Sci Rep
. 2017 Mar;
7:44619.
PMID: 28317930
Fluorescence microscopy is rapidly turning into nanoscopy. Among the various nanoscopy methods, the STED/RESOLFT super-resolution family has recently been expanded to image even large fields of view within a few...
3.
Schonle A, Von Middendorff C, Ringemann C, Hell S, Eggeling C
Microsc Res Tech
. 2014 Apr;
77(7):528-36.
PMID: 24729575
A marker's dark triplet state is of great importance in fluorescence microscopy: It serves as a means to switch off fluorescent markers and is thus the enabling element for several...
4.
Vicidomini G, Schonle A, Ta H, Han K, Moneron G, Eggeling C, et al.
PLoS One
. 2013 Jan;
8(1):e54421.
PMID: 23349884
In a stimulated emission depletion (STED) microscope the region in which fluorescence markers can emit spontaneously shrinks with continued STED beam action after a singular excitation event. This fact has...
5.
Wildanger D, Patton B, Schill H, Marseglia L, Hadden J, Knauer S, et al.
Adv Mater
. 2012 Sep;
24(44):OP309-13.
PMID: 22968917
Exploring the maximum spatial resolution achievable in far-field optical imaging, we show that applying solid immersion lenses (SIL) in stimulated emission depletion (STED) microscopy addresses single spins with a resolution...
6.
Geisler C, Hotz T, Schonle A, Hell S, Munk A, Egner A
Opt Express
. 2012 Mar;
20(7):7274-89.
PMID: 22453409
In recent years, the diffraction barrier in fluorescence imaging has been broken and optical nanoscopes now routinely image with resolutions of down to 20 nm, an improvement of more than...
7.
Aquino D, Schonle A, Geisler C, Middendorff C, Wurm C, Okamura Y, et al.
Nat Methods
. 2011 Mar;
8(4):353-9.
PMID: 21399636
We demonstrate three-dimensional (3D) super-resolution imaging of stochastically switched fluorophores distributed across whole cells. By evaluating the higher moments of the diffraction spot provided by a 4Pi detection scheme, single...
8.
Testa I, Wurm C, Medda R, Rothermel E, von Middendorf C, Folling J, et al.
Biophys J
. 2010 Oct;
99(8):2686-94.
PMID: 20959110
Current far-field fluorescence nanoscopes provide subdiffraction resolution by exploiting a mechanism of fluorescence inhibition. This mechanism is implemented such that features closer than the diffraction limit emit separately when simultaneously...
9.
Kamin D, Lauterbach M, Westphal V, Keller J, Schonle A, Hell S, et al.
Biophys J
. 2010 Jul;
99(2):675-84.
PMID: 20643088
Synaptic vesicles need to be mobile to reach their release sites during synaptic activity. We investigated vesicle mobility throughout the synaptic vesicle cycle using both conventional and subdiffraction-resolution stimulated emission...
10.
Vicidomini G, Schmidt R, Egner A, Hell S, Schonle A
Opt Express
. 2010 Jul;
18(10):10154-67.
PMID: 20588870
4Pi-microscopy doubles the aperture of the imaging system by coherent addition of the wavefronts for illumination and/or detection through opposing objective lenses. This improves the axial resolution 3-7 fold, but...