Andreas S Thum
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Explore the profile of Andreas S Thum including associated specialties, affiliations and a list of published articles.
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47
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1345
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Recent Articles
1.
Korner M, Velluva A, Bundalian L, Krohn K, Schon K, Schumann I, et al.
J Neurogenet
. 2025 Feb;
:1-16.
PMID: 40000652
Pathogenic variants in , a gene encoding for an autophagy adaptor termed ALFY, are linked to neurodevelopmental delay and altered brain size in human probands. While the role of loss-of-function...
2.
Vieira Contreras F, Auger G, Muller L, Richter V, Huetteroth W, Seufert F, et al.
Cell Rep
. 2024 Jan;
43(1):113640.
PMID: 38180839
Adhesion G-protein-coupled receptors (aGPCRs) form a large family of cell surface molecules with versatile tasks in organ development. Many aGPCRs still await their functional and pharmacological deorphanization. Here, we characterized...
3.
Mancini N, Thoener J, Tafani E, Pauls D, Mayseless O, Strauch M, et al.
J Neurosci
. 2023 Sep;
43(44):7393-7428.
PMID: 37734947
Larvae of the fruit fly are a powerful study case for understanding the neural circuits underlying behavior. Indeed, the numerical simplicity of the larval brain has permitted the reconstruction of...
4.
Poe A, Zhu L, Szuperak M, McClanahan P, Anafi R, Scholl B, et al.
Sci Adv
. 2023 Sep;
9(36):eadh2301.
PMID: 37683005
In adulthood, sleep-wake rhythms are one of the most prominent behaviors under circadian control. However, during early life, sleep is spread across the 24-hour day. The mechanism through which sleep...
5.
Thum A, Gerber B
Elife
. 2023 Mar;
12.
PMID: 36867155
The way neurons in the brain rewire in larvae as they turn to adult fruit flies sheds light on how complete metamorphosis was 'invented' over the course of evolution.
6.
Weber D, Richter V, Rohwedder A, Grossjohann A, Thum A
Cold Spring Harb Protoc
. 2022 Sep;
2023(3):108050-pdb.prot.
PMID: 36180215
larvae are able to associate an odor stimulus with a temporally overlapping teaching signal encoding reward or punishment. Here, we describe a standardized experimental setup that allows the analysis of...
7.
Weber D, Richter V, Rohwedder A, Grossjohann A, Thum A
Cold Spring Harb Protoc
. 2022 Sep;
2023(3):107863-pdb.top.
PMID: 36180213
The larva has become an attractive model system for studying fundamental questions in neuroscience. Although the focus was initially on topics such as the structure of genes, mechanisms of inheritance,...
8.
Hernandez-Nunez L, Chen A, Budelli G, Berck M, Richter V, Rist A, et al.
Sci Adv
. 2021 Aug;
7(35).
PMID: 34452914
Body temperature homeostasis is essential and reliant upon the integration of outputs from multiple classes of cooling- and warming-responsive cells. The computations that integrate these outputs are not understood. Here,...
9.
Schumann I, Berger M, Nowag N, Schafer Y, Saumweber J, Scholz H, et al.
Sci Rep
. 2021 Jun;
11(1):12307.
PMID: 34112872
Chemosensory signals allow vertebrates and invertebrates not only to orient in its environment toward energy-rich food sources to maintain nutrition but also to avoid unpleasant or even poisonous substrates. Ethanol...
10.
Meloni I, Sachidanandan D, Thum A, Kittel R, Murawski C
Sci Rep
. 2020 Oct;
10(1):17614.
PMID: 33077824
Invertebrates such as Drosophila melanogaster have proven to be a valuable model organism for studies of the nervous system. In order to control neuronal activity, optogenetics has evolved as a...