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Andreas Roetzer

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Articles 19
Citations 1044
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Recent Articles
1.
Schoergenhofer C, Gelbenegger G, Hasanacevic D, Schoner L, Steiner M, Firbas C, et al.
EClinicalMedicine . 2024 Jan; 67:102404. PMID: 38274114
Background: Toxic shock syndrome toxin-1 (TSST-1) is a superantigen produced by that causes the life-threatening toxic shock syndrome. The development of a safe and immunogenic vaccine against TSST-1 remains an...
2.
Roetzer A, Model N, Laube J, Unterhumer Y, Haller G, Eibl M
Toxins (Basel) . 2022 Sep; 14(9). PMID: 36136533
is a human and animal pathogen as well as a commensal bacterium. It can be a causative agent of severe, life-threatening infections with high mortality, e.g., toxic shock syndrome, septic...
3.
Roetzer A, Stich N, Model N, Schwameis M, Firbas C, Jilma B, et al.
Toxins (Basel) . 2020 Oct; 12(10). PMID: 33023185
Staphylococcal superantigen toxins lead to a devastating cytokine storm resulting in shock and multi-organ failure. We have previously assessed the safety and immunogenicity of a recombinant toxic shock syndrome toxin...
4.
Roetzer A, Jilma B, Eibl M
Expert Rev Vaccines . 2016 Dec; 16(2):81-83. PMID: 27918218
No abstract available.
5.
Roetzer A, Gruener C, Haller G, Beyerly J, Model N, Eibl M
Toxins (Basel) . 2016 Nov; 8(11). PMID: 27801832
Among the toxin family of bacterial superantigens, the six members of the enterotoxin gene cluster (egc) seem to have unusual characteristics. They are present in the majority of strains, but...
6.
Schwameis M, Roppenser B, Firbas C, Gruener C, Model N, Stich N, et al.
Lancet Infect Dis . 2016 Jun; 16(9):1036-1044. PMID: 27296693
Background: Staphylococcal toxic shock syndrome is a superantigen-driven potentially life-threatening disease affecting mainly young and otherwise healthy individuals. Currently, no specific treatment or preventive measure is available. We aimed to...
7.
Roetzer A, Haller G, Beyerly J, Geier C, Wolf H, Gruener C, et al.
BMC Microbiol . 2016 Feb; 16:13. PMID: 26830934
Background: Nosocomial infections caused by the bacterial pathogen Staphylococcus aureus can lead to serious complications due to the varying presence of secreted toxins. Comparative studies of genomic information and production...
8.
Merker M, Kohl T, Roetzer A, Truebe L, Richter E, Rusch-Gerdes S, et al.
PLoS One . 2013 Dec; 8(12):e82551. PMID: 24324807
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effective, resulting in a significant number of...
9.
Roetzer A, Diel R, Kohl T, Ruckert C, Nubel U, Blom J, et al.
PLoS Med . 2013 Feb; 10(2):e1001387. PMID: 23424287
Background: Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient discriminatory power to resolve large outbreaks. Here, we tested the potential...
10.
Reiter W, Klopf E, De Wever V, Anrather D, Petryshyn A, Roetzer A, et al.
Mol Cell Biol . 2013 Jan; 33(5):1057-72. PMID: 23275436
We have identified Cdc55, a regulatory B subunit of protein phosphatase 2A (PP2A), as an essential activating factor for stress gene transcription in Saccharomyces cerevisiae. The presence of PP2A-Cdc55 is...