Andreas Hober
Overview
Explore the profile of Andreas Hober including associated specialties, affiliations and a list of published articles.
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17
Citations
554
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Recent Articles
1.
Lofgren L, von Euler Chelpin M, Bhat M, Althage M, Hober A, Edfors F, et al.
J Appl Lab Med
. 2023 Dec;
9(2):329-341.
PMID: 38113397
Background: Developing and implementing new patient-centric strategies for drug trials lowers the barrier to participation for some patients by reducing the need to travel to research sites. In early chronic...
2.
Kotol D, Woessmann J, Hober A, Alvez M, Tran Minh K, Ponten F, et al.
Cancers (Basel)
. 2023 Oct;
15(19).
PMID: 37835457
Mass spectrometry based on data-independent acquisition (DIA) has developed into a powerful quantitative tool with a variety of implications, including precision medicine. Combined with stable isotope recombinant protein standards, this...
3.
Woessmann J, Petrosius V, Uresin N, Kotol D, Aragon-Fernandez P, Hober A, et al.
Anal Chem
. 2023 Aug;
95(36):13649-13658.
PMID: 37639361
Mass spectrometry-based bottom-up proteomics is rapidly evolving and routinely applied in large-scale biomedical studies. Proteases are a central component of every bottom-up proteomics experiment, digesting proteins into peptides. Trypsin has...
4.
Johansson C, Hunt H, Signorelli M, Edfors F, Hober A, Svensson A, et al.
Clin Proteomics
. 2023 Jun;
20(1):23.
PMID: 37308827
Background: Molecular components in blood, such as proteins, are used as biomarkers to detect or predict disease states, guide clinical interventions and aid in the development of therapies. While multiplexing...
5.
Hober A, Rekanovic M, Forsstrom B, Hansson S, Kotol D, Percy A, et al.
PLoS One
. 2023 Feb;
18(2):e0281772.
PMID: 36791076
Lipoprotein(a), also known as Lp(a), is an LDL-like particle composed of apolipoprotein(a) (apo(a)) bound covalently to apolipoprotein B100. Plasma concentrations of Lp(a) are highly heritable and vary widely between individuals....
6.
Woessmann J, Kotol D, Hober A, Uhlen M, Edfors F
J Proteome Res
. 2022 Aug;
21(10):2526-2534.
PMID: 36044728
Protein quantification strategies using multiple proteases have been shown to deliver poor interprotease accuracy in label-free mass spectrometry experiments. By utilizing six different proteases with different cleavage sites, this study...
7.
Saghaleyni R, Malm M, Moruzzi N, Zrimec J, Razavi R, Wistbacka N, et al.
Cell Rep
. 2022 Jun;
39(11):110936.
PMID: 35705050
Recombinant protein production can cause severe stress on cellular metabolism, resulting in limited titer and product quality. To investigate cellular and metabolic characteristics associated with these limitations, we compare HEK293...
8.
Hober A, Tran-Minh K, Foley D, McDonald T, Vissers J, Pattison R, et al.
Elife
. 2021 Nov;
10.
PMID: 34747696
Reliable, robust, large-scale molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for monitoring the ongoing coronavirus disease 2019 (COVID-19) pandemic. We have developed a scalable analytical...
9.
Jahn M, Crang N, Janasch M, Hober A, Forsstrom B, Kimler K, et al.
Elife
. 2021 Nov;
10.
PMID: 34723797
Bacteria must balance the different needs for substrate assimilation, growth functions, and resilience in order to thrive in their environment. Of all cellular macromolecules, the bacterial proteome is by far...
10.
Kotol D, Hober A, Strandberg L, Svensson A, Uhlen M, Edfors F
Biotechniques
. 2021 Aug;
71(3):473-483.
PMID: 34431357
Targeted proteomics is an attractive approach for the analysis of blood proteins. Here, we describe a novel analytical platform based on isotope-labeled recombinant protein standards stored in a chaotropic agent...