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Andreas Hiergeist

Explore the profile of Andreas Hiergeist including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 1038
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Recent Articles
1.
Fischer L, Paschke B, Gareis F, Schumacher M, Liere P, Hiergeist A, et al.
Neuropharmacology . 2024 Dec; 266():110282. PMID: 39725124
The treatment of stress-related disorders such as anxiety and depression is still challenging. One potential therapeutical option are neurosteroids. Their synthesis is promoted by ligands of the mitochondrial translocator protein...
2.
Turner A, Li L, Monk I, Lee J, Ingle D, Portelli S, et al.
Nature . 2024 Oct; 635(8040):969-977. PMID: 39443798
Multidrug-resistant bacterial pathogens like vancomycin-resistant Enterococcus faecium (VREfm) are a critical threat to human health. Daptomycin is a last-resort antibiotic for VREfm infections with a novel mode of action, but...
3.
Alt V, Gessner A, Merabishvili M, Hitzenbichler F, Mannala G, Peterhoff D, et al.
Front Med (Lausanne) . 2024 Jul; 11:1428432. PMID: 39071087
Fracture-related infections can be challenging, particularly with concomitant severe bone defects and multi-resistant microorganisms. We present a case of a 42-year-old patient with a fracture-related infection following a war injury...
4.
Huss A, Bachhuber F, Feraudet-Tarisse C, Hiergeist A, Tumani H
Biomedicines . 2024 Jul; 12(7). PMID: 39061966
Recent research has suggested a link between multiple sclerosis and the gut microbiota. This prospective pilot study aimed to investigate the composition of the gut microbiota in MS patients, the...
5.
Weber D, Meedt E, Poeck H, Thiele-Orberg E, Hiergeist A, Gessner A, et al.
Visc Med . 2024 Jul; :1-6. PMID: 39047173
Background: Acute graft-versus-host disease (GvHD) is a major and sometimes lethal complication following allogeneic stem cell transplantation (aSCT). In the last 10 years, a massive loss of microbiota diversity with...
6.
Kremser M, Weiss N, Kaufmann-Stoeck A, Vierbaum L, Kappler S, Schellenberg I, et al.
Front Mol Biosci . 2024 Apr; 11:1373114. PMID: 38601324
Background: Quality control (QC), quality assurance, and standardization are crucial for modern diagnostic testing in the field of medical microbiology. The need for efficient QC to ensure accurate laboratory results,...
7.
Schreiber L, Ghimire S, Hiergeist A, Renner K, Althammer M, Babl N, et al.
Front Immunol . 2024 Mar; 15:1347835. PMID: 38495883
Vitamin D3 regulates a variety of biological processes irrespective of its well-known importance for calcium metabolism. Epidemiological and animal studies indicate a role in immune regulation, intestinal barrier function and...
8.
Bulow S, Ederer K, Holzinger J, Zeller L, Werner M, Toelge M, et al.
Cell Rep . 2024 Mar; 43(3):113929. PMID: 38457343
Neutrophil-derived bactericidal/permeability-increasing protein (BPI) is known for its bactericidal activity against gram-negative bacteria and neutralization of lipopolysaccharide. Here, we define BPI as a potent activator of murine dendritic cells (DCs)....
9.
Thiele Orberg E, Meedt E, Hiergeist A, Xue J, Heinrich P, Ru J, et al.
Nat Cancer . 2024 Jan; 5(1):187-208. PMID: 38172339
The microbiome is a predictor of clinical outcome in patients receiving allogeneic hematopoietic stem cell transplantation (allo-SCT). Microbiota-derived metabolites can modulate these outcomes. How bacteria, fungi and viruses contribute to...
10.
Manook A, Baghai T, Riebel M, Nothdurfter C, Schwarzbach J, Gessner A, et al.
Front Neurosci . 2023 Dec; 17:1188847. PMID: 38075272
Background: Neurosteroids have recently gained in interest as a treatment strategy for affective disorders. Etifoxine is known for its dual mode of action, one of which is to stimulate endogenous...