Andreas C Themistocleous
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Explore the profile of Andreas C Themistocleous including associated specialties, affiliations and a list of published articles.
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42
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1228
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Recent Articles
11.
Baskozos G, Themistocleous A, Hebert H, Pascal M, John J, Callaghan B, et al.
BMC Med Inform Decis Mak
. 2022 Jun;
22(1):144.
PMID: 35644620
Background: To improve the treatment of painful Diabetic Peripheral Neuropathy (DPN) and associated co-morbidities, a better understanding of the pathophysiology and risk factors for painful DPN is required. Using harmonised...
12.
Wesselink D, Sanders Z, Edmondson L, Dempsey-Jones H, Kieliba P, Kikkert S, et al.
Sci Adv
. 2022 Apr;
8(16):eabk2393.
PMID: 35452294
Electrophysiological studies in monkeys show that finger amputation triggers local remapping within the deprived primary somatosensory cortex (S1). Human neuroimaging research, however, shows persistent S1 representation of the missing hand's...
13.
Themistocleous A, Kristensen A, Sola R, Gylfadottir S, Bennedsgaard K, Itani M, et al.
Ann Neurol
. 2022 Feb;
91(4):506-520.
PMID: 35150149
Objective: Axonal excitability reflects ion channel function, and it is proposed that this may be a biomarker in painful (vs painless) polyneuropathy. Our objective was to investigate the relationship between...
14.
Middleton S, Perini I, Themistocleous A, Weir G, McCann K, Barry A, et al.
Brain
. 2021 Dec;
145(10):3637-3653.
PMID: 34957475
Patients with bi-allelic loss of function mutations in the voltage-gated sodium channel Nav1.7 present with congenital insensitivity to pain (CIP), whilst low threshold mechanosensation is reportedly normal. Using psychophysics (n...
15.
Ramanathan S, Tseng M, Davies A, Uy C, Paneva S, Mgbachi V, et al.
Ann Neurol
. 2021 Aug;
90(4):683-690.
PMID: 34370313
Pain is a under-recognized association of leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) antibodies. Of 147 patients with these autoantibodies, pain was experienced by 17 of 33 (52%)...
16.
Middleton S, Barry A, Comini M, Li Y, Ray P, Shiers S, et al.
Brain
. 2021 Jun;
144(5):1312-1335.
PMID: 34128530
Chronic pain affects one in five of the general population and is the third most important cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate due to poor efficacy and...
17.
Jensen T, Karlsson P, Gylfadottir S, Andersen S, Bennett D, Tankisi H, et al.
Brain
. 2021 Mar;
144(6):1632-1645.
PMID: 33711103
Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. Up to half of patients with diabetes develop neuropathy during the course of...
18.
Karlsson P, Gylfadottir S, Kristensen A, Ramirez J, Cruz P, Le N, et al.
Diabetologia
. 2021 Jan;
64(4):923-931.
PMID: 33483760
Aims/hypothesis: Distal diabetic sensorimotor polyneuropathy (DSP) is a common complication of diabetes with many patients showing a reduction of intraepidermal nerve fibre density (IENFD) from skin biopsy, a validated and...
19.
Bennedsgaard K, Ventzel L, Andersen N, Themistocleous A, Bennett D, Jensen T, et al.
J Peripher Nerv Syst
. 2020 Sep;
25(4):377-387.
PMID: 32902058
The aim of this study was to evaluate the presence and characterization of chemotherapy-induced neuropathy (CIPN) and neuropathic pain 5 years after adjuvant chemotherapy with docetaxel or oxaliplatin. Patients from...
20.
Turro E, Astle W, Megy K, Graf S, Greene D, Shamardina O, et al.
Nature
. 2020 Jun;
583(7814):96-102.
PMID: 32581362
Most patients with rare diseases do not receive a molecular diagnosis and the aetiological variants and causative genes for more than half such disorders remain to be discovered. Here we...