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Andreas Bergmann

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Articles 237
Citations 8514
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Recent Articles
1.
Ilina Y, Kaufmann P, Press M, Uba T, Bergmann A
Biomolecules . 2025 Feb; 15(2). PMID: 40001527
Peptidylglycine alpha-amidating monooxygenase (PAM) is the only enzyme known to catalyze C-terminal amidation, a final post-translational modification step essential for the biological activity of over 70 bioactive peptides, including adrenomedullin...
2.
McGovern-Gooch K, Mani N, Gotchev D, Ardzinski A, Kowalski R, Sheraz M, et al.
Antiviral Res . 2024 Nov; 232:106038. PMID: 39577571
Since the SARS-CoV-2 outbreak, there have been ongoing efforts to identify antiviral molecules with broad coronavirus activity to combat COVID-19. SARS-CoV-2's main protease (M) is responsible for processing the viral...
3.
Kaufmann P, Ilina Y, Press M, Bergmann A
Sci Rep . 2024 Nov; 14(1):28091. PMID: 39543387
Adrenomedullin (ADM) is a multifaceted peptide hormone involved in numerous physiological processes, including vascular stability, vasodilation, angiogenesis, and anti-inflammatory responses. The processing of ADM results in several fragments, including midregional...
4.
Yarikipati P, Bergmann A
Elife . 2024 Nov; 13. PMID: 39494688
An enzyme known as caspase, which initiates apoptosis, has a central role in the regeneration of cells and repair of tissue that can occur after necrosis.
5.
Rai P, Bergmann A
Front Cell Dev Biol . 2024 Oct; 12:1479864. PMID: 39411483
Protein aggregation is a common pathological occurrence in neurodegenerative diseases. This often leads to neuroinflammation, which exacerbates the aggregation and progression of diseases like Parkinson's and Alzheimer's. Here, we focus...
6.
Braun T, Afgin N, Sapozhnikov L, Sivan E, Bergmann A, Baena-Lopez L, et al.
bioRxiv . 2024 Sep; PMID: 39282309
Caspases, well-known for their role in executing apoptosis, also participate in various non-apoptotic processes. Despite this, their involvement in promoting compensatory proliferation - a key aspect of tissue regeneration following...
7.
Wenzl F, Wang P, Arrigo M, Parenica J, Jones D, Bruno F, et al.
Eur Heart J . 2024 Aug; 46(1):38-54. PMID: 39215600
Background And Aims: Circulating proenkephalin (PENK) is a stable endogenous polypeptide with fast response to glomerular dysfunction and tubular damage. This study examined the predictive value of PENK for renal...
8.
Giontella A, Akerlund M, Bronton K, Fava C, Lotta L, Baras A, et al.
J Clin Endocrinol Metab . 2024 Aug; 110(3):820-829. PMID: 39137152
Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. Objective: To define the clinical phenotype of carriers of genetic...
9.
Runarsson T, Bergmann A, Erlingsdottir G, Petursdottir V, Heitmann L, Johannesson A, et al.
BMC Urol . 2024 May; 24(1):105. PMID: 38741053
Introduction: Papillary renal cell carcinoma (pRCC) is the second most common histology of renal cell carcinoma (RCC), accounting for 10-15% of cases. Traditionally, pRCC is divided into type 1 and...
10.
Jujic A, Molvin J, Nilsson E, Isholth H, Dieden A, Korduner J, et al.
J Card Fail . 2024 Feb; 30(11):1452-1461. PMID: 38364966
Background: Selenoprotein P (SELENOP) is a transporter for selenium and has been shown to protect selenium-status maintenance in the brain against deficiency and to support neuronal development, neurogenesis and neurocognitive...