Andrea Nans
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Explore the profile of Andrea Nans including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
973
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Recent Articles
1.
Drobnic T, Cohen E, Calcraft T, Alzheimer M, Froschauer K, Svensson S, et al.
bioRxiv
. 2024 Oct;
PMID: 39416179
One hurdle to understanding how molecular machines work, and how they evolve, is our inability to see their structures . Here we describe a minicell system that enables cryogenic electron...
2.
Henrikus S, Gross M, Willhoft O, Puhringer T, Lewis J, McClure A, et al.
Nat Struct Mol Biol
. 2024 Sep;
31(11):1808.
PMID: 39251823
No abstract available.
3.
Calcraft T, Stanke-Scheffler N, Nans A, Lindemann D, Taylor I, Rosenthal P
Cell
. 2024 Jul;
187(16):4213-4230.e19.
PMID: 39013471
Foamy viruses (FVs) are an ancient lineage of retroviruses, with an evolutionary history spanning over 450 million years. Vector systems based on Prototype Foamy Virus (PFV) are promising candidates for...
4.
Henrikus S, Gross M, Willhoft O, Puhringer T, Lewis J, McClure A, et al.
Nat Struct Mol Biol
. 2024 May;
31(8):1265-1276.
PMID: 38760633
To prevent detrimental chromosome re-replication, DNA loading of a double hexamer of the minichromosome maintenance (MCM) replicative helicase is temporally separated from DNA unwinding. Upon S-phase transition in yeast, DNA...
5.
Acton O, Sheppard D, Kunzelmann S, Caswell S, Nans A, Burgess A, et al.
Nat Commun
. 2024 May;
15(1):3775.
PMID: 38710701
SAMHD1 regulates cellular nucleotide homeostasis, controlling dNTP levels by catalysing their hydrolysis into 2'-deoxynucleosides and triphosphate. In differentiated CD4+ macrophage and resting T-cells SAMHD1 activity results in the inhibition of...
6.
Griffith S, Muir L, Suchanek O, Hope J, Pade C, Gibbons J, et al.
bioRxiv
. 2024 Feb;
PMID: 38370662
Immunological determinants favouring emergence of broadly neutralising antibodies are crucial to the development of HIV-1 vaccination strategies. Here, we combined RNAseq and B cell cloning approaches to isolate a broadly...
7.
Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal P, Way M
mBio
. 2024 Jan;
15(2):e0313423.
PMID: 38171004
Vaccinia virus assembly in the cytoplasm of infected cells involves the formation of a biconcave viral core inside the maturing viral particle. The boundary of the core is defined by...
8.
Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal P, Way M
PLoS Biol
. 2023 Mar;
21(3):e3002005.
PMID: 36862727
During its cytoplasmic replication, vaccinia virus assembles non-infectious spherical immature virions (IV) coated by a viral D13 lattice. Subsequently, IV mature into infectious brick-shaped intracellular mature virions (IMV) that lack...
9.
Lewis J, Gross M, Sousa J, Henrikus S, Greiwe J, Nans A, et al.
Nature
. 2022 Jun;
606(7916):1007-1014.
PMID: 35705812
The activation of eukaryotic origins of replication occurs in temporally separated steps to ensure that chromosomes are copied only once per cell cycle. First, the MCM helicase is loaded onto...
10.
Ballandras-Colas A, Chivukula V, Gruszka D, Shan Z, Singh P, Pye V, et al.
Nat Commun
. 2022 May;
13(1):2416.
PMID: 35504909
A multimer of retroviral integrase (IN) synapses viral DNA ends within a stable intasome nucleoprotein complex for integration into a host cell genome. Reconstitution of the intasome from the maedi-visna...