Andrea Kerkhoff
Overview
Explore the profile of Andrea Kerkhoff including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
398
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0
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Recent Articles
1.
Functional apoptosis profiling reveals vulnerabilities in T-cell large granular lymphocytic leukemia
Shumilov E, Mazzeo P, Trautmann M, Levien L, Menck K, Richter K, et al.
Ann Hematol
. 2025 Feb;
104(1):581-591.
PMID: 39912943
T-cell large granular lymphocytic leukemia (T-LGLL) is a rare hematologic neoplasm characterized by clonal expansion of CD3 + cytotoxic T lymphocytes and a highly heterogeneous clinical course. Conventional therapy primarily...
2.
Shumilov E, Wurm-Kuczera R, Kerkhoff A, Wang M, Melchardt T, Holtick U, et al.
Blood Adv
. 2024 Dec;
PMID: 39661985
Glofitamab, a bispecific antibody targeting CD20 and CD3, is approved for relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL) after at least two prior treatment lines, but real-world data is scarce....
3.
Borchmann P, Ferdinandus J, Schneider G, Moccia A, Greil R, Hertzberg M, et al.
Lancet
. 2024 Jul;
404(10450):341-352.
PMID: 38971175
Background: Intensified systemic chemotherapy has the highest primary cure rate for advanced-stage, classical Hodgkin lymphoma but this comes with a cost of severe and potentially life long, persisting toxicities. With...
4.
Aydilek E, Wulf G, Schwarz F, Bacher U, Rummel M, Stiefel O, et al.
Cancer Med
. 2024 May;
13(10):e7289.
PMID: 38770551
Background: Mantle cell lymphoma (MCL) is a type of B-cell lymphoma that is currently incurable. Pirtobrutinib shows promising response rates in heavily pretreated MCL patients according to the approval study,...
5.
Dreyling M, Doorduijn J, Gine E, Jerkeman M, Walewski J, Hutchings M, et al.
Lancet
. 2024 May;
403(10441):2293-2306.
PMID: 38705160
Background: Adding ibrutinib to standard immunochemotherapy might improve outcomes and challenge autologous stem-cell transplantation (ASCT) in younger (aged 65 years or younger) mantle cell lymphoma patients. This trial aimed to...
6.
Berning P, Shumilov E, Maulhardt M, Boyadzhiev H, Kerkhoff A, Call S, et al.
Hemasphere
. 2024 Mar;
8(3):e54.
PMID: 38510993
CD19-directed chimeric antigen receptor (CAR)-T cell therapy has become a standard treatment for relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). While the benefits of CAR-T cell treatment are clear in...
7.
Schorb E, Isbell L, Kerkhoff A, Mathas S, Braulke F, Egerer G, et al.
Lancet Haematol
. 2024 Feb;
11(3):e196-e205.
PMID: 38301670
Background: Available treatments for older patients with primary diffuse large B-cell CNS lymphoma (PCNSL) offer progression-free survival of up to 16 months. We aimed to investigate an intensified treatment of...
8.
Shumilov E, Mazzeo P, Ghandili S, Kunstner A, Weidemann S, Banz Y, et al.
Ann Hematol
. 2024 Jan;
103(5):1587-1599.
PMID: 38194088
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare malignancy derived from plasmacytoid dendritic cells, can mimic both acute leukemia and aggressive T-cell lymphoma. Therapy of this highly aggressive hematological disease...
9.
Krekeler C, Wethmar K, Mikesch J, Kerkhoff A, Menck K, Lenz G, et al.
Int J Mol Sci
. 2023 Aug;
24(15).
PMID: 37569431
DNA mismatch repair deficient (dMMR) and microsatellite instable (MSI) metastatic colorectal cancer (mCRC) can be successfully treated with FDA- and EMA-approved immune checkpoint inhibitors (ICI) pembrolizumab and nivolumab (as single...
10.
Kroger K, Siats J, Kerkhoff A, Lenz G, Stelljes M, Eich H, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765940
Introduction: In patients with mantle cell lymphoma (MCL), long-term remissions can be achieved by stem cell transplantation (SCT). Different conditioning treatment protocols exist with or without total body irradiation (TBI)....