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Andrea Heinz

Explore the profile of Andrea Heinz including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 733
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Recent Articles
1.
Stec A, Heinz A, Dziomba S
J Pharm Anal . 2025 Jan; 14(12):101004. PMID: 39802401
Extracellular vesicles (EVs) are a part of a cell-to-cell communication system of prokaryotic and eukaryotic organisms. Their ability to penetrate biological barriers and to transfer molecules between cells shows their...
2.
Stec A, Targonska M, Jaikishan S, Chen R, Mucha P, Czyrski G, et al.
Drug Deliv . 2024 Dec; 32(1):2439272. PMID: 39663752
Extracellular vesicles (EVs) are an experimental class of drug carriers. Alternative sources of EVs are currently being explored to overcome limitations related to their manufacturing from mesenchymal stem cells. In...
3.
Czyrski G, Frese Hjort M, Rades T, Heinz A
Eur J Pharm Biopharm . 2024 Nov; 205:114576. PMID: 39522705
Transdermal delivery of therapeutic molecules is often hindered by the properties of the skin, with the stratum corneum serving as the primary permeation barrier. To overcome this barrier, the integrity...
4.
Gurtler A, Lang J, Czyrski G, Sirois J, Melican K, Rades T, et al.
Biomater Adv . 2024 Oct; 166:214068. PMID: 39413707
In this proof-of-concept study, we aimed to develop an anti-inflammatory patch that in contrast to the semi-solid standard therapy is dry and non-greasy, and only needs to be changed once...
5.
Gade L, Boyd B, Malmsten M, Heinz A
Acta Biomater . 2024 Aug; 187:1-19. PMID: 39209132
Inflammatory skin conditions highly influence the quality of life of the patients suffering from these disorders. Symptoms include red, itchy and painful skin lesions, which are visible to the rest...
6.
Czyrski G, Rades T, Heinz A
Int J Pharm . 2024 Aug; 664:124615. PMID: 39168288
Terpene-based eutectic mixtures (EMs) are attractive platforms for transdermal delivery due to their solubilizing potential and ability to alter the barrier function of the stratum corneum (SC). Despite this, little...
7.
Gurtler A, Maltschik A, M Guler Yildiz S, Vangelofski K, Gade L, Grohganz H, et al.
Eur J Pharm Biopharm . 2024 Jul; 202:114423. PMID: 39038523
Inflammatory skin diseases are typically managed with semi-solid formulations such as creams and ointments. These treatments often fail to remain on the skin for long, as they can be easily...
8.
Sirois J, Heinz A
Pharmacol Ther . 2024 Jun; 260:108682. PMID: 38917886
The extracellular matrix (ECM) represents a complex multi-component environment that has a decisive influence on the biomechanical properties of tissues and organs. Depending on the tissue, ECM components are subject...
9.
Be Rzins K, Czyrski G, Aljabbari A, Heinz A, Boyd B
Anal Chem . 2024 Apr; 96(16):6408-6416. PMID: 38602505
The noninvasive monitoring of the status of drug retention and implant integrity of subcutaneous implants would allow optimization of therapy and avoid periods of subtherapeutic delivery kinetics. A proof-of principle...
10.
Noddeland H, Canbay V, Lind M, Savickas S, Jensen L, Petersson K, et al.
Biochimie . 2024 Mar; 226:99-106. PMID: 38513823
Inflammation and autoimmunity are known as central processes in many skin diseases, including psoriasis. It is therefore important to develop pre-clinical models that describe disease-related aspects to enable testing of...