Andrea Castro
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Explore the profile of Andrea Castro including associated specialties, affiliations and a list of published articles.
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Citations
443
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Recent Articles
1.
Bendik J, Castro A, Califano J, Carter H, Guo T
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796063
The discovery of tumor-derived neoantigens which elicit an immune response through major histocompatibility complex (MHC-I/II) binding has led to significant advancements in immunotherapy. While many neoantigens have been discovered through...
2.
Sears T, Pagadala M, Castro A, Lee K, Kong J, Tanaka K, et al.
Cancer Immunol Res
. 2024 Sep;
12(12):1780-1795.
PMID: 39255339
Immune checkpoint blockade (ICB) has revolutionized cancer treatment; however, the mechanisms determining patient response remain poorly understood. Here, we used machine learning to predict ICB response from germline and somatic...
3.
Castro A, Lardone M, Giraudo F, Lopez P, Ortiz E, Iniguez G, et al.
J Endocr Soc
. 2024 Jun;
8(7):bvae091.
PMID: 38883396
Context: Adolescents and young women (AYA) with type 1 diabetes (T1D) may require hormonal contraception for an extended period. However, it is unclear what effect hormonal contraception has on telomere...
4.
Sears T, Pagadala M, Castro A, Lee K, Kong J, Tanaka K, et al.
bioRxiv
. 2024 Jan;
PMID: 38293085
Immune Checkpoint Blockade (ICB) has revolutionized cancer treatment, however mechanisms determining patient response remain poorly understood. Here we used machine learning to predict ICB response from germline and somatic biomarkers...
5.
Giraudo F, Salinas A, Merino P, Iniguez G, Lopez P, Castro A, et al.
J Pediatr Adolesc Gynecol
. 2023 Nov;
37(2):177-183.
PMID: 38012981
Study Objective: To determine the metabolic effects of the subcutaneous etonogestrel implant compared with an oral contraceptive in adolescents and young adults (AYAs) with type 1 diabetes (T1D) on body...
6.
Castro A, Goodman A, Rane Z, Talwar J, Frampton G, Morris G, et al.
J Immunother Precis Oncol
. 2023 Aug;
6(3):127-132.
PMID: 37637234
Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can cure patients with high-risk myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). However, many patients relapse or develop debilitating graft-versus-host disease. Transplant...
7.
Rodriguez F, Godoy M, Ortiz E, Benitez-Filselcker A, Lopez M, Cassorla F, et al.
Andrology
. 2023 Jun;
12(2):289-296.
PMID: 37377277
Background: Cryptorchidism is one of the most common congenital disorders in boys and it is associated with a higher risk of sub-fertility and testicular cancer. Testicular descent occurs during embryo-fetal...
8.
Talwar J, Laub D, Pagadala M, Castro A, Lewis M, Luebeck G, et al.
Am J Hum Genet
. 2023 Jun;
110(7):1138-1161.
PMID: 37339630
Autoimmunity and cancer represent two different aspects of immune dysfunction. Autoimmunity is characterized by breakdowns in immune self-tolerance, while impaired immune surveillance can allow for tumorigenesis. The class I major...
9.
Gruen C, Yang H, Sassano A, Wu E, Gopalan V, Marie K, et al.
bioRxiv
. 2023 Jun;
PMID: 37333132
Intratumoral heterogeneity (ITH) can promote cancer progression and treatment failure, but the complexity of the regulatory programs and contextual factors involved complicates its study. To understand the specific contribution of...
10.
Pagadala M, Sears T, Wu V, Perez-Guijarro E, Kim H, Castro A, et al.
Nat Commun
. 2023 May;
14(1):2744.
PMID: 37173324
With the continued promise of immunotherapy for treating cancer, understanding how host genetics contributes to the tumor immune microenvironment (TIME) is essential to tailoring cancer screening and treatment strategies. Here,...