Andre van Helvoort Lengert
Overview
Explore the profile of Andre van Helvoort Lengert including associated specialties, affiliations and a list of published articles.
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26
Citations
236
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Recent Articles
1.
Serpeloni J, da Silva I, van Helvoort Lengert A, Souza M, Dos Reis M, Kuasne H, et al.
Gene
. 2024 Dec;
939:149158.
PMID: 39706230
Background: Alteration in DNA repair and metabolism genes can affect the maintenance of DNA integrity or xenobiotics metabolism, potentially leading to DNA damage accumulation. The present study investigated the association...
2.
Cardoso I, Rosa M, Moreno D, Tufi L, Ramos L, Pereira L, et al.
Mol Med Rep
. 2024 Oct;
30(6).
PMID: 39392037
Germ cell tumors (GCTs) constitute diverse neoplasms arising in the gonads or extragonadal locations. Testicular GCTs (TGCTs) are the predominant solid tumors in adolescents and young men. Despite cisplatin serving...
3.
Pontes J, Jadranin M, Assalin M, Quintero Escobar M, Stanisic D, Carneiro Costa T, et al.
Metabolites
. 2024 Aug;
14(8).
PMID: 39195512
Cancer is a complex disease that can also affect the younger population; however, it is responsible for a relatively high mortality rate of children and youth, especially in low- and...
4.
van Helvoort Lengert A, Tassinari T, Lourenco A, Peronni K, Castro P, Pereira J, et al.
Diagn Microbiol Infect Dis
. 2024 Aug;
110(3):116426.
PMID: 39163789
Blood culture, the gold-standard method for identifying pathogens in bloodstream infections, is time-consuming and demonstrates low sensitivity. These drawbacks are related to high mortality, especially among pediatric oncology patients presenting...
5.
Santarosa Vieira A, Sussuchi da Silva L, da Silva E, Laus A, Faria T, van Helvoort Lengert A, et al.
Mol Oncol
. 2024 May;
18(6):1593-1607.
PMID: 38725152
microRNAs (miRNAs) are small endogenous noncoding RNAs, and alterations in their expression may contribute to oncogenesis. Discovering a unique miRNA pattern holds the potential for early detection and novel treatment...
6.
Ribeiro D, Latancia M, de Souza I, Ariwoola A, Mendes D, Rocha C, et al.
Biosci Rep
. 2024 May;
44(5).
PMID: 38717250
Temozolomide (TMZ) is the leading therapeutic agent for combating Glioblastoma Multiforme (GBM). Nonetheless, the persistence of chemotherapy-resistant GBM cells remains an ongoing challenge, attributed to various factors, including the translesion...
7.
Pires S, Sobral de Barros J, da Costa S, Carmo G, Scliar M, van Helvoort Lengert A, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445641
Osteosarcoma (OS) is the most prevalent type of bone tumor, but slow progress has been achieved in disentangling the full set of genomic events involved in its initiation and progression....
8.
Ramos C, Oliveira R, Rosa M, Pereira A, de Abreu R, van Helvoort Lengert A, et al.
Curr Cancer Drug Targets
. 2023 Apr;
23(11):900-909.
PMID: 37076963
Background: Breast and ovarian tumors with pathogenic variants in or genes are more sensitive to poly (ADP-ribose) polymerase inhibitors (PARPi) treatment than wildtype tumors. Pathogenic variants in non- homologous recombination...
9.
Causin R, van Helvoort Lengert A, Gomes I, Freitas A, Rosa M, Dos Reis R, et al.
Oncol Rep
. 2023 Apr;
49(5).
PMID: 37052265
MicroRNAs (miRNAs or miRs) play essential roles in the initiation and progression of human tumors, including cervical cancer. However, the mechanisms underlying their actions in cervical cancer remain unclear. The...
10.
Pires S, Sobral de Barros J, da Costa S, Scliar M, van Helvoort Lengert A, Boldrini E, et al.
Mol Genet Genomics
. 2023 Apr;
298(3):721-733.
PMID: 37020053
DNA methylation may be involved in the development of osteosarcomas. Osteosarcomas commonly arise during the bone growth and remodeling in puberty, making it plausible to infer the involvement of epigenetic...