Andre M Miranda
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Explore the profile of Andre M Miranda including associated specialties, affiliations and a list of published articles.
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6
Citations
193
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Recent Articles
1.
Kalinichenko L, Muhle C, Jia T, Anderheiden F, Datz M, Eberle A, et al.
Cereb Cortex
. 2022 Mar;
33(3):844-864.
PMID: 35296883
Alcohol use, abuse, and addiction, and resulting health hazards are highly sex-dependent with unknown mechanisms. Previously, strong links between the SMPD3 gene and its coded protein neutral sphingomyelinase 2 (NSM)...
2.
Kalinichenko L, Muhle C, Jia T, Anderheiden F, Datz M, Eberle A, et al.
Mol Psychiatry
. 2021 Sep;
26(12):7403-7416.
PMID: 34584229
Mental disorders are highly comorbid and occur together with physical diseases, which are often considered to arise from separate pathogenic pathways. We observed in alcohol-dependent patients increased serum activity of...
3.
Miranda A, Paolo G
Cell Stress
. 2019 Jun;
2(5):115-118.
PMID: 31225476
Growing evidence suggests that endolysosomal and autophagic defects are key pathogenic processes in various neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), frontotemporal dementia (FTD) and amyotrophic lateral sclerosis...
4.
Miranda A, Herman M, Cheng R, Nahmani E, Barrett G, Micevska E, et al.
Cell Rep
. 2018 Jun;
23(10):2967-2975.
PMID: 29874583
The phosphoinositide phosphatase synaptojanin 1 (SYNJ1) is a key regulator of synaptic function. We first tested whether SYNJ1 contributes to phenotypic variations in familial Alzheimer's disease (FAD) and show that...
5.
Miranda A, Lasiecka Z, Xu Y, Neufeld J, Shahriar S, Simoes S, et al.
Nat Commun
. 2018 Jan;
9(1):291.
PMID: 29348617
Defects in endolysosomal and autophagic functions are increasingly viewed as key pathological features of neurodegenerative disorders. A master regulator of these functions is phosphatidylinositol-3-phosphate (PI3P), a phospholipid synthesized primarily by...
6.
Williamson R, Laulagnier K, Miranda A, Fernandez M, Wolfe M, Sadoul R, et al.
J Biol Chem
. 2017 Oct;
292(48):19873-19889.
PMID: 29021256
Amyloid plaques, a neuropathological hallmark of Alzheimer's disease, are largely composed of amyloid β (Aβ) peptide, derived from cleavage of amyloid precursor protein (APP) by β- and γ-secretases. The endosome...