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Andre Dagenais

Explore the profile of Andre Dagenais including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 395
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Recent Articles
1.
Aubin Vega M, Chupin C, Masse C, Dagenais A, Berthiaume Y, Brochiero E
Exp Physiol . 2021 Jan; 106(4):1110-1119. PMID: 33502034
New Findings: What is the central question of this study? How does the downregulation of ENaC, the major driving force for alveolar fluid clearance, impact acute lung injury outcomes induced...
2.
Migneault F, Gagnon F, Brochiero E, Berthiaume Y, Dagenais A
J Vis Exp . 2020 Mar; (157). PMID: 32202533
Studying posttranscriptional regulation is fundamental to understanding the modulation of a given messenger RNA (mRNA) and its impact on cell homeostasis and metabolism. Indeed, fluctuations in transcript expression could modify...
3.
Aubin Vega M, Chupin C, Pascariu M, Prive A, Dagenais A, Berthiaume Y, et al.
Physiol Rep . 2019 Nov; 7(21):e14253. PMID: 31724341
Acute respiratory distress syndrome (ARDS) features an exudative phase characterized by alveolar damage, lung edema and exacerbated inflammatory response. Given their anti-inflammatory properties, the potential therapeutic effect of corticosteroids has...
4.
Migneault F, Gagnon F, Pascariu M, Laperle J, Roy A, Dagenais A, et al.
Cell Physiol Biochem . 2019 Apr; 52(5):984-1002. PMID: 30977984
Background/aims: The epithelial sodium channel (ENaC) expressed in alveolar epithelial cells plays a major role in lung liquid clearance at birth and lung edema resorption in adulthood. We showed previously...
5.
Dagenais A, Desjardins J, Shabbir W, Roy A, Filion D, Sauve R, et al.
Pflugers Arch . 2018 Aug; 470(11):1615-1631. PMID: 30088081
The epithelial Na channel (ENaC) plays an essential role in lung physiology by modulating the amount of liquid lining the respiratory epithelium. Here, we tested the effect of breaking alveolar...
6.
Voisin G, Bouvet G, Legendre P, Dagenais A, Masse C, Berthiaume Y
Physiol Genomics . 2014 Jun; 46(17):634-46. PMID: 24893876
Although cystic fibrosis (CF) pathophysiology is explained by a defect in CF transmembrane conductance regulator (CFTR) protein, the broad spectrum of disease severity is the consequence of environmental and genetic...
7.
Migneault F, Boncoeur E, Morneau F, Pascariu M, Dagenais A, Berthiaume Y
Am J Physiol Lung Cell Mol Physiol . 2013 Sep; 305(10):L747-55. PMID: 24039256
Active Na(+) transport mediated by epithelial Na(+) channel (ENaC) is vital for fetal lung fluid reabsorption at birth and pulmonary edema resolution. Previously, we demonstrated that αENaC expression and activity...
8.
Dagenais A, Tessier M, Tatur S, Brochiero E, Grygorczyk R, Berthiaume Y
PLoS One . 2013 Sep; 8(9):e74565. PMID: 24019969
Alveolar epithelial cells are involved in Na(+) absorption via the epithelial Na(+) channel (ENaC), an important process for maintaining an appropriate volume of liquid lining the respiratory epithelium and for...
9.
Boncoeur E, Bouvet G, Migneault F, Tardif V, Ferraro P, Radzioch D, et al.
Am J Physiol Lung Cell Mol Physiol . 2013 May; 305(2):L175-84. PMID: 23686852
Nitric oxide (NO) plays an important role in innate host defense and inflammation. In response to infection, NO is generated by inducible nitric oxide synthase (iNOS), a gene product whose...
10.
Bardou O, Prive A, Migneault F, Roy-Camille K, Dagenais A, Berthiaume Y, et al.
Biochim Biophys Acta . 2012 Mar; 1818(7):1682-90. PMID: 22406554
Active Na+ absorption by alveolar ENaC is the main driving force of liquid clearance at birth and lung edema resorption in adulthood. We have demonstrated previously that long-term modulation of...