Andras Bilkei-Gorzo
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Explore the profile of Andras Bilkei-Gorzo including associated specialties, affiliations and a list of published articles.
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65
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1510
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Recent Articles
1.
Oddi S, Scipioni L, Totaro A, Giacovazzo G, Ciaramellano F, Tortolani D, et al.
FEBS J
. 2025 Jan;
PMID: 39822137
The endocannabinoid N-arachidonoylethanolamine (AEA) is a pro-homeostatic bioactive lipid known for its anti-inflammatory, anti-oxidative, immunomodulatory, and neuroprotective properties, which may contrast/mitigate Alzheimer's disease (AD) pathology. This study explores the therapeutic...
2.
Bilkei-Gorzo A, Schurmann B, Schneider M, Kraemer M, Nidadavolu P, Beins E, et al.
ACS Pharmacol Transl Sci
. 2024 Sep;
7(9):2637-2649.
PMID: 39296258
Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR) has a major impact on aging by regulating cellular...
3.
Palmisano M, Ramunno C, Farhat E, Dvir-Ginzberg M, Lutz B, Ruiz de Almodovar C, et al.
Mech Ageing Dev
. 2024 May;
220:111954.
PMID: 38821184
As organisms age, the activity of the endocannabinoid system in the brain declines, coinciding with increased neuroinflammation and disrupted hypothalamic functions. Notably, cannabinoid receptors type-1 (CB1) are highly expressed in...
4.
Gargano A, Olabiyi B, Palmisano M, Zimmer A, Bilkei-Gorzo A
Front Neurosci
. 2023 Sep;
17:1264253.
PMID: 37694113
Introduction: Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted that age-related histological changes such as increased neuroinflammatory glial activity and a...
5.
Timmermann A, Tascio D, Jabs R, Boehlen A, Domingos C, Skubal M, et al.
Glia
. 2023 Feb;
71(6):1481-1501.
PMID: 36802096
NG2 glia represents a distinct type of macroglial cells in the CNS and is unique among glia because they receive synaptic input from neurons. They are abundantly present in white...
6.
Komorowska-Muller J, Gellner A, Ravichandran K, Bilkei-Gorzo A, Zimmer A, Stein V
Sci Rep
. 2023 Jan;
13(1):1390.
PMID: 36697430
Cognitive functions decline during aging. This decline could be caused by changes in dendritic spine stability and altered spine dynamics. Previously, we have shown that a low dose chronic THC ...
7.
Palmisano M, Gargano A, Olabiyi B, Lutz B, Bilkei-Gorzo A
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36613469
Endocannabinoid system activity declines with age in the hippocampus, along with the density of the cannabinoid receptor type-1 (CB1). This process might contribute to brain ageing, as previous studies showed...
8.
Carmon I, Zecharyahu L, Elayyan J, Meka S, Reich E, Kandel L, et al.
J Bone Miner Res
. 2022 Nov;
38(1):154-170.
PMID: 36350089
Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study aimed to assess the effect and mechanism of action of HU308,...
9.
Nidadavolu P, Bilkei-Gorzo A, Effah F, Leidmaa E, Schurmann B, Berger M, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142165
Endocannabinoid (eCB) signaling is markedly decreased in the hippocampus (Hip) of aged mice, and the genetic deletion of the cannabinoid receptor type 1 (CB1) leads to an early onset of...
10.
Schuele L, Schuermann B, Bilkei-Gorzo A, Gorgzadeh S, Zimmer A, Leidmaa E
Sci Rep
. 2022 Jan;
12(1):633.
PMID: 35022487
The endocannabinoid system modulates adult hippocampal neurogenesis by promoting the proliferation and survival of neural stem and progenitor cells (NSPCs). This is demonstrated by the disruption of adult neurogenesis under...