Anderson H F F Leao
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Explore the profile of Anderson H F F Leao including associated specialties, affiliations and a list of published articles.
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14
Citations
180
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Recent Articles
1.
Vrechi T, Guarache G, Oliveira R, Guedes E, Erustes A, Leao A, et al.
Neurotox Res
. 2025 Feb;
43(1):8.
PMID: 39900844
Tau is a neuronal protein that confers stability to microtubules; however, its hyperphosphorylation and accumulation can lead to an impairment of protein degradation pathways, such as autophagy. Autophagy is a...
2.
Sperandio L, Lins I, Erustes A, Leao A, Antunes F, Morais I, et al.
Toxicol In Vitro
. 2023 Apr;
90:105603.
PMID: 37121360
Sorafenib, an oral multi-kinase inhibitor, used to treat hepatocellular carcinoma (HCC). However, drug resistance is still common in several HCC patients. This complex mechanism is not yet fully elucidated, driving...
3.
Guedes E, Erustes A, Leao A, Carneiro C, Abilio V, Zuardi A, et al.
Neurochem Res
. 2023 Mar;
48(8):2390-2405.
PMID: 36964823
Progressive neurodegenerative disorders such as Parkinson Disease (PD) lack curative or long-term treatments. At the same time, the increase of the worldwide elderly population and, consequently, the extension in the...
4.
Kurita J, Leao A, Bioni V, Wuo-Silva R, Lima A, Paiva-Santos M, et al.
Behav Neurosci
. 2022 Dec;
137(2):143-153.
PMID: 36548050
Optimal levels of anxiety are critical to memory consolidation, but maladaptive anxiety can disrupt memory acquisition. Serotonergic activity within the amygdala influences both anxiety-like behavior and aversive memory consolidation. To...
5.
Paiva-Santos M, Leao A, Kurita J, Becegato M, Lima A, Bioni V, et al.
Behav Pharmacol
. 2022 May;
33(5):322-332.
PMID: 35502955
Effects of acute ethanol (EtOH) on memory depend on several factors, including type of behavioral task. Sex differences in EtOH effects have been reported in humans and animals, and recognition...
6.
Leao A, Meurer Y, Freitas T, Medeiros A, Abilio V, Izidio G, et al.
Behav Brain Res
. 2021 May;
410:113349.
PMID: 33971246
Reserpine (RES) is an irreversible inhibitor of VMAT2 used to study Parkinson's disease (PD) and screening for antiparkinsonian treatments in rodents. Recently, the repeated treatment with a low dose of...
7.
Vrechi T, Leao A, Morais I, Abilio V, Zuardi A, Hallak J, et al.
Sci Rep
. 2021 Mar;
11(1):5434.
PMID: 33686185
Autophagy is a lysosomal catabolic process essential to cell homeostasis and is related to the neuroprotection of the central nervous system. Cannabidiol (CBD) is a non-psychotropic phytocannabinoid present in Cannabis...
8.
Becegato M, Meurer Y, Paiva-Santos M, Lima A, Marinho G, Bioni V, et al.
Physiol Behav
. 2021 Feb;
232:113343.
PMID: 33529686
Historically, females have been neglected in behavioral neuroscience research due to the alleged increased variability caused by hormonal fluctuations. More recently, there has been a tendency to include female subjects...
9.
Beserra-Filho J, de Macedo A, Leao A, Bispo J, Santos J, de Oliveira-Melo A, et al.
Food Chem Toxicol
. 2018 Nov;
124:17-29.
PMID: 30481574
Evidence indicates that oxidative stress has an important role in the onset and progression of Parkinson's disease (PD). Antioxidant agents from natural products have shown neuroprotective effects in animal models...
10.
Leao A, Meurer Y, da Silva A, Medeiros A, Campelo C, Abilio V, et al.
Front Aging Neurosci
. 2017 Apr;
9:78.
PMID: 28396635
Reserpine is an irreversible inhibitor of vesicular monoamine transporter-2 (VMAT2) used to study Parkinson's disease (PD) and screening for antiparkinsonian treatments in rodents. Recently, the repeated treatment with a low-dose...