Anastasia Gurinovich
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Explore the profile of Anastasia Gurinovich including associated specialties, affiliations and a list of published articles.
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27
Citations
371
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Recent Articles
1.
Hummer B, Sebastiani P, Leshchyk A, Gurinovich A, Bager C, Karsdal M, et al.
bioRxiv
. 2025 Jan;
PMID: 39763916
Dupuytren Disease (DD) is a chronic progressive disease that can cause disabling hand deformities. The most common treatments have high rates of complications and early recurrence. Dupuytren lacks a staging...
2.
Gurinovich A, Song Z, Bae H, Leshchyk A, Li M, Lords H, et al.
Geroscience
. 2025 Jan;
PMID: 39751714
Using whole-genome sequencing (WGS) might offer insights into rare genetic variants associated with healthy aging and extreme longevity (EL), potentially pointing to useful therapeutic targets. In this study, we conducted...
3.
Sebastiani P, Monti S, Lustgarten M, Song Z, Ellis D, Tian Q, et al.
Cell Rep
. 2024 Nov;
43(11):114913.
PMID: 39504246
Metabolites that mark aging are not fully known. We analyze 408 plasma metabolites in Long Life Family Study participants to characterize markers of age, aging, extreme longevity, and mortality. We...
4.
Li M, Song Z, Gurinovich A, Schork N, Sebastiani P, Monti S
PLoS One
. 2024 Jun;
19(6):e0298501.
PMID: 38833463
Quantitative trait loci (QTL) denote regions of DNA whose variation is associated with variations in quantitative traits. QTL discovery is a powerful approach to understand how changes in molecular and...
5.
Li M, Song Z, Gurinovich A, Schork N, Sebastiani P, Monti S
bioRxiv
. 2024 Feb;
PMID: 38370654
Quantitative trait loci (QTL) denote regions of DNA whose variation is associated with variations in quantitative traits. QTL discovery is a powerful approach to understand how changes in molecular and...
6.
Estabrooks T, Gurinovich A, Pietruska J, Lewis B, Harvey G, Post G, et al.
Vet Comp Oncol
. 2023 Sep;
21(4):623-633.
PMID: 37734854
Canine hemangiosarcoma (HSA) is an aggressive cancer of endothelial cells with short survival times. Understanding the genomic landscape of HSA may aid in developing therapeutic strategies for dogs and may...
7.
Leshchyk A, Xiang Q, Andersen S, Gurinovich A, Song Z, Lee J, et al.
J Gerontol A Biol Sci Med Sci
. 2023 Mar;
78(9):1561-1568.
PMID: 36988570
Mosaic chromosomal alterations (mCAs) are structural alterations associated with aging, cancer, cardiovascular disease, infectious diseases, and mortality. The distribution of mCAs in centenarians and individuals with familial longevity is poorly...
8.
Song Z, Gurinovich A, Nygaard M, Mengel-From J, Andersen S, Cosentino S, et al.
Neurobiol Aging
. 2023 Feb;
125:115-122.
PMID: 36813607
We conducted a genome-wide association study of Digit Symbol Substitution Test scores administered in 4207 family members of the Long Life Family Study (LLFS). Genotype data were imputed to the...
9.
Bae H, Gurinovich A, Karagiannis T, Song Z, Leshchyk A, Li M, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36613555
We performed a genome-wide association study (GWAS) of human extreme longevity (EL), defined as surviving past the 99th survival percentile, by aggregating data from four centenarian studies. The combined data...
10.
Gurinovich A, Li M, Leshchyk A, Bae H, Song Z, Arbeev K, et al.
Front Genet
. 2022 Oct;
13:897210.
PMID: 36212134
Performing a genome-wide association study (GWAS) with a binary phenotype using family data is a challenging task. Using linear mixed effects models is typically unsuitable for binary traits, and numerical...