Ananthakrishnan Sankaranarayanan
Overview
Explore the profile of Ananthakrishnan Sankaranarayanan including associated specialties, affiliations and a list of published articles.
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8
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797
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Recent Articles
1.
Weed P, Leonard S, Sankaranarayanan A, Winsauer P
J Exp Anal Behav
. 2014 Jan;
101(2):303-15.
PMID: 24446273
Mephedrone (4-methylmethcathinone) has been found in several over-the-counter products that are abused by humans, but very little is known about its behavioral effects and abuse liability. The present study examined...
2.
Varner K, Daigle K, Weed P, Lewis P, Mahne S, Sankaranarayanan A, et al.
Psychopharmacology (Berl)
. 2012 Sep;
225(3):675-85.
PMID: 22972412
Rationale: Exceedingly little experimental research exists on the popular recreational drug mephedrone (4-methylmethcathinone) despite clinical reports concerning its behavioral and cardiovascular toxicity. Objectives: To characterize mephedrone preclinically by examining its...
3.
Shakkottai V, Costa M, DellOrco J, Sankaranarayanan A, Wulff H, Paulson H
J Neurosci
. 2011 Sep;
31(36):13002-14.
PMID: 21900579
The relationship between cerebellar dysfunction, motor symptoms, and neuronal loss in the inherited ataxias, including the polyglutamine disease spinocerebellar ataxia type 3 (SCA3), remains poorly understood. We demonstrate that before...
4.
Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin P, Hoyer J, et al.
Mol Pharmacol
. 2008 Oct;
75(2):281-95.
PMID: 18955585
Small-conductance (KCa2.1-2.3) and intermediate-conductance (KCa3.1) calcium-activated K(+) channels are critically involved in modulating calcium-signaling cascades and membrane potential in both excitable and nonexcitable cells. Activators of these channels constitute useful...
5.
Wulff H, Kolski-Andreaco A, Sankaranarayanan A, Sabatier J, Shakkottai V
Curr Med Chem
. 2007 Jun;
14(13):1437-57.
PMID: 17584055
Calcium-activated potassium channels modulate calcium signaling cascades and membrane potential in both excitable and non-excitable cells. In this article we will review the physiological properties, the structure activity relationships of...
6.
Azam P, Sankaranarayanan A, Homerick D, Griffey S, Wulff H
J Invest Dermatol
. 2007 Feb;
127(6):1419-29.
PMID: 17273162
The voltage-gated potassium channel Kv1.3 has been recently identified as a molecular target that allows for selective pharmacological suppression of effector memory T (T(EM)) cells without affecting the function of...
7.
Beeton C, Wulff H, Standifer N, Azam P, Mullen K, Pennington M, et al.
Proc Natl Acad Sci U S A
. 2006 Nov;
103(46):17414-9.
PMID: 17088564
Autoreactive memory T lymphocytes are implicated in the pathogenesis of autoimmune diseases. Here we demonstrate that disease-associated autoreactive T cells from patients with type-1 diabetes mellitus or rheumatoid arthritis (RA)...
8.
Schmitz A, Sankaranarayanan A, Azam P, Schmidt-Lassen K, Homerick D, Hansel W, et al.
Mol Pharmacol
. 2005 Aug;
68(5):1254-70.
PMID: 16099841
The lymphocyte K+ channel Kv1.3 constitutes an attractive pharmacological target for the selective suppression of terminally differentiated effector memory T (TEM) cells in T cell-mediated autoimmune diseases, such as multiple...