Ana R Rodriguez
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Explore the profile of Ana R Rodriguez including associated specialties, affiliations and a list of published articles.
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19
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274
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Recent Articles
1.
Simard M, Nshimiyimana R, Chiang N, Rodriguez A, Spur B, Serhan C
Sci Adv
. 2024 Nov;
10(47):eadq4785.
PMID: 39565847
Production of specialized proresolving mediators (SPMs) during the resolution phase in the acute inflammatory response is key to orchestrating complete resolution. Here, we uncovered a trihydroxy resolvin in fresh human...
2.
Nshimiyimana R, Simard M, Teder T, Rodriguez A, Spur B, Haeggstrom J, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(37):e2405821121.
PMID: 39236243
While the acute inflammatory response to harmful stimuli is protective, unrestrained neutrophil swarming drives collateral tissue damage and inflammation. Biosynthesized from omega-3 essential polyunsaturated fatty acids, resolvins are a family...
3.
ONeill K, Anderson E, Mukherjee S, Gandu S, McEwan S, Omelchenko A, et al.
Commun Biol
. 2023 Dec;
6(1):1278.
PMID: 38110605
Plasticity and homeostatic mechanisms allow neural networks to maintain proper function while responding to physiological challenges. Despite previous work investigating morphological and synaptic effects of brain-derived neurotrophic factor (BDNF), the...
4.
Nshimiyimana R, Libreros S, Simard M, Chiang N, Rodriguez A, Spur B, et al.
Am J Hematol
. 2023 May;
98(7):1000-1016.
PMID: 37139907
Specialized pro-resolving lipid mediators play key functions in the resolution of the acute inflammatory response. Herein, we elucidate the stereochemical structure of the new 4S,5R-RCTR1, a cysteinyl-resolvin, recently uncovered in...
5.
Pistorius K, Ly L, Souza P, Gomez E, Koenis D, Rodriguez A, et al.
EBioMedicine
. 2022 Apr;
79:103974.
PMID: 35430453
Background: Rheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered...
6.
Chiang N, Sakuma M, Rodriguez A, Spur B, Irimia D, Serhan C
Blood
. 2021 Nov;
139(8):1222-1233.
PMID: 34814186
The newly identified 13-series (T-series) resolvins (RvTs) regulate phagocyte functions and accelerate resolution of infectious inflammation. Because severe acute respiratory syndrome coronavirus 2 elicits uncontrolled inflammation involving neutrophil extracellular traps...
7.
Rodriguez A, Anderson E, ONeill K, McEwan P, Vigilante N, Kwon M, et al.
Netw Neurosci
. 2021 Mar;
5(1):166-197.
PMID: 33688611
Cytosolic PSD-95 interactor (cypin) regulates many aspects of neuronal development and function, ranging from dendritogenesis to synaptic protein localization. While it is known that removal of postsynaptic density protein-95 (PSD-95)...
8.
Rodriguez A, Spur B
Tetrahedron Lett
. 2020 Sep;
61(20).
PMID: 32863450
The first total synthesis of the pro-resolving lipid mediator 7(),12(),13()-Resolvin T2 [7(), 12(), 13()-RvT2] and its 13()-epimer, derived from n-3 docosapentaenoic acid (n-3 DPA), are described. 7(), 12(), 13()-RvT2 and...
9.
Rodriguez A, Spur B
Tetrahedron Lett
. 2020 Apr;
61(6).
PMID: 32313313
The first total syntheses of the pro-resolving lipid mediators 7(),13(),20()-Resolvin T1 [7(),13(),20()-RvT1] and 7(),13()-Resolvin T4 [7(),13()-RvT4], derived from n-3 docosapentaenoic acid (n-3 DPA), are described. 7(),13(),20()-RvT1 was prepared from 7(),13()-RvT4...
10.
De La Rosa X, Norris P, Chiang N, Rodriguez A, Spur B, Serhan C
Am J Pathol
. 2018 Mar;
188(4):950-966.
PMID: 29571326
Resolvin conjugates in tissue regeneration (RCTRs) are new chemical signals that accelerate resolution of inflammation, infection, and tissue regeneration. Herein, using liquid chromatography-tandem mass spectrometry-based metabololipidomics, we identified RCTRs in...