Ana R Machado-Santos
Overview
Explore the profile of Ana R Machado-Santos including associated specialties, affiliations and a list of published articles.
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5
Citations
87
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Recent Articles
1.
Machado-Santos A, Loureiro-Campos E, Patricio P, Araujo B, Alves N, Mateus-Pinheiro A, et al.
Cells
. 2022 Feb;
11(3).
PMID: 35159199
Depression is a prevalent, socially burdensome disease. Different studies have demonstrated the important role of astrocytes in the pathophysiology of depression as modulators of neurotransmission and neurovascular coupling. This is...
2.
Machado-Santos A, Alves N, Araujo B, Correia J, Patricio P, Mateus-Pinheiro A, et al.
Neuroscience
. 2019 Nov;
454:94-104.
PMID: 31747562
Astrocytes are now known to play crucial roles in the central nervous system, supporting and closely interacting with neurons and therefore able to modulate brain function. Both human postmortem studies...
3.
Alves N, Patricio P, Correia J, Mateus-Pinheiro A, Machado-Santos A, Loureiro-Campos E, et al.
Brain Struct Funct
. 2017 Aug;
223(1):415-428.
PMID: 28852856
The continuous generation of new neurons and glial cells in the adult hippocampal dentate gyrus (DG) represents an important form of adult neuroplasticity, involved in normal brain function and behavior...
4.
Patricio P, Mateus-Pinheiro A, Irmler M, Alves N, Machado-Santos A, Morais M, et al.
Neuropsychopharmacology
. 2014 Jul;
40(2):338-49.
PMID: 25035085
Major depression is a highly prevalent, multidimensional disorder. Although several classes of antidepressants (ADs) are currently available, treatment efficacy is limited, and relapse rates are high; thus, there is a...
5.
Mateus-Pinheiro A, Patricio P, Alves N, Machado-Santos A, Morais M, Bessa J, et al.
Front Behav Neurosci
. 2014 Mar;
8:74.
PMID: 24639637
Measuring anhedonic behavior in rodents is a challenging task as current methods display only moderate sensitivity to detect anhedonic phenotype and, consequently, results from different labs are frequently incongruent. Herein...