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Ana Mrejeru

Explore the profile of Ana Mrejeru including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 907
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Recent Articles
1.
Chung S, Kishinevsky S, Mazzulli J, Graziotto J, Mrejeru A, Mosharov E, et al.
Stem Cell Reports . 2016 Sep; 7(4):664-677. PMID: 27641647
Parkinson's disease (PD) is characterized by the selective loss of dopamine neurons in the substantia nigra; however, the mechanism of neurodegeneration in PD remains unclear. A subset of familial PD...
2.
Avegno E, Salling M, Borgkvist A, Mrejeru A, Whitebirch A, Margolis E, et al.
Neuropharmacology . 2016 Aug; 110(Pt A):386-395. PMID: 27475082
Enhanced dopamine (DA) neurotransmission from the ventral tegmental area (VTA) to the ventral striatum is thought to drive drug self-administration and mediate positive reinforcement. We examined neuronal firing rates in...
3.
Wu J, Hussaini S, Bastille I, Rodriguez G, Mrejeru A, Rilett K, et al.
Nat Neurosci . 2016 Jun; 19(8):1085-92. PMID: 27322420
Tau protein can transfer between neurons transneuronally and trans-synaptically, which is thought to explain the progressive spread of tauopathy observed in the brain of patients with Alzheimer's disease. Here we...
4.
Steinbeck J, Choi S, Mrejeru A, Ganat Y, Deisseroth K, Sulzer D, et al.
Nat Biotechnol . 2015 Jan; 33(2):204-9. PMID: 25580598
Recent studies have shown evidence of behavioral recovery after transplantation of human pluripotent stem cell (PSC)-derived neural cells in animal models of neurological disease. However, little is known about the...
5.
Schmitz Y, Castagna C, Mrejeru A, Lizardi-Ortiz J, Klein Z, Lindsley C, et al.
J Neurosci . 2013 Oct; 33(42):16778-89. PMID: 24133278
NMDA receptor activity is involved in shaping synaptic connections throughout development and adulthood. We recently reported that brief activation of NMDA receptors on cultured ventral midbrain dopamine neurons enhanced their...
6.
Crone S, Viemari J, Droho S, Mrejeru A, Ramirez J, Sharma K
J Neurosci . 2012 Jun; 32(23):7895-906. PMID: 22674265
Neural networks called central pattern generators (CPGs) generate repetitive motor behaviors such as locomotion and breathing. Glutamatergic neurons are required for the generation and inhibitory neurons for the patterning of...
7.
Borgkvist A, Mrejeru A, Sulzer D
Neuron . 2011 Jun; 70(5):803-5. PMID: 21658574
A small number of ventral tegmental area dopamine neurons engage in numerous and apparently contradictory functions--how can this be? A clue is provided by Lammel and colleagues in this issue...
8.
Mrejeru A, Wei A, Ramirez J
J Physiol . 2011 Apr; 589(Pt 10):2497-514. PMID: 21486760
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst...
9.
Marcuccilli C, Tryba A, van Drongelen W, Koch H, Viemari J, Pena-Ortega F, et al.
J Clin Neurophysiol . 2010 Nov; 27(6):387-97. PMID: 21076335
To test the hypothesis that focal and parafocal neocortical tissue from pediatric patients with intractable epilepsy exhibits cellular and synaptic differences, the authors characterized the propensity of these neurons to...
10.
Frazier C, Mrejeru A
J Neurosci . 2010 Jul; 30(30):9964-6. PMID: 20668180
No abstract available.