Ana Martin-Villalba
Overview
Explore the profile of Ana Martin-Villalba including associated specialties, affiliations and a list of published articles.
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59
Citations
2340
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Recent Articles
1.
Kremer L, Cerrizuela S, El-Sammak H, Al Shukairi M, Ellinger T, Straub J, et al.
Nature
. 2024 Sep;
634(8033):415-423.
PMID: 39232166
Astrocytes are the most abundant cell type in the mammalian brain and provide structural and metabolic support to neurons, regulate synapses and become reactive after injury and disease. However, a...
2.
Kremer L, Braun M, Ovchinnikova S, Kuchenhoff L, Cerrizuela S, Martin-Villalba A, et al.
Nat Methods
. 2024 Jul;
21(9):1616-1623.
PMID: 39085432
Single-cell bisulfite sequencing (scBS) is a technique that enables the assessment of DNA methylation at single-base pair and single-cell resolution. The analysis of large datasets obtained from scBS requires preprocessing...
3.
Zehrer A, Martin-Villalba A, Diederich B, Ewers H
Elife
. 2024 Mar;
12.
PMID: 38436658
Fluorescence microscopy is a fundamental tool in the life sciences, but the availability of sophisticated equipment required to yield high-quality, quantitative data is a major bottleneck in data production in...
4.
Ciriello G, Magnani L, Aitken S, Akkari L, Behjati S, Hanahan D, et al.
Cancer Discov
. 2023 Dec;
14(1):36-48.
PMID: 38047596
Significance: Tumor evolution is fueled by multiple enabling mechanisms. Importantly, genetic instability, epigenetic reprogramming, and interactions with the tumor microenvironment are neither alternative nor independent evolutionary mechanisms. As demonstrated by...
5.
Danciu D, Hooli J, Martin-Villalba A, Marciniak-Czochra A
Cells Dev
. 2023 May;
174:203849.
PMID: 37179018
Adult stem cells are described as a discrete population of cells that stand at the top of a hierarchy of progressively differentiating cells. Through their unique ability to self-renew and...
6.
Carvajal Ibanez D, Skabkin M, Hooli J, Cerrizuela S, Gopferich M, Jolly A, et al.
EMBO Mol Med
. 2023 Jan;
15(4):e16434.
PMID: 36636818
Stem cells show intrinsic interferon signalling, which protects them from viral infections at all ages. In the ageing brain, interferon signalling also reduces the ability of stem cells to activate....
7.
Kutz S, Zehrer A, Svetlitckii R, Gulculer Balta G, Galli L, Kleber S, et al.
Front Bioinform
. 2022 Oct;
1:723915.
PMID: 36303736
Ligand binding of membrane proteins triggers many important cellular signaling events by the lateral aggregation of ligand-bound and other membrane proteins in the plane of the plasma membrane. This local...
8.
Figlia G, Muller S, Hagenston A, Kleber S, Roiuk M, Quast J, et al.
Nat Cell Biol
. 2022 Sep;
24(9):1407-1421.
PMID: 36097071
Mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient availability to appropriately regulate cellular anabolism and catabolism. During nutrient restriction, different organs in an animal do not respond equally, with...
9.
Cerrizuela S, Kaya O, Kremer L, Sarvari A, Ellinger T, Straub J, et al.
STAR Protoc
. 2022 Sep;
3(3):101555.
PMID: 36072757
Single-cell nucleosome, methylome, and transcriptome (scNMT) sequencing is a recently developed method that allows multiomics profiling of single cells. In this scNMT protocol, we describe profiling of cells from mouse...
10.
Dang H, Martin-Villalba A, Schiebel E
EMBO Rep
. 2022 May;
23(7):e53805.
PMID: 35599622
The centrosome linker component C-Nap1 (encoded by CEP250) anchors filaments to centrioles that provide centrosome cohesion by connecting the two centrosomes of an interphase cell into a single microtubule organizing...