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Ana Grenha

Explore the profile of Ana Grenha including associated specialties, affiliations and a list of published articles. Areas
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Articles 46
Citations 782
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Recent Articles
1.
Pontes J, Diogo H, Conceicao E, Almeida M, Borges Dos Santos R, Grenha A
Eur J Pharm Sci . 2024 Apr; 197:106775. PMID: 38643941
Research on pharmaceutical dry powders has been increasing worldwide, along with increased therapeutic strategies for an application through the pulmonary or the nasal routes. In vitro methodologies and tests that...
2.
Guerreiro F, Pontes J, Gaspar M, Rosa da Costa A, Faleiro M, Grenha A
Int J Biol Macromol . 2023 Jul; 248:125838. PMID: 37455007
Pulmonary delivery of drugs is potentially beneficial in the context of lung disease, maximising drug concentrations in the site of action. A recent work proposed spray-dried konjac glucomannan (KGM) microparticles...
3.
Florez-Fernandez N, Pontes J, Guerreiro F, Afonso I, Lollo G, Torres M, et al.
Mar Drugs . 2023 Feb; 21(2). PMID: 36827156
The composition of seaweeds is complex, with vitamins, phenolic compounds, minerals, and polysaccharides being some of the factions comprising their structure. The main polysaccharide in brown seaweeds is fucoidan, and...
4.
Grenha A, Guerreiro F, Lourenco J, Lopes J, Camara-Martos F
Food Chem . 2022 Oct; 402:134463. PMID: 36303366
Se in the form of sodium selenite was microencapsulated by spray - drying and added to a food matrix (yogurt) to study the potential improvement of its bioaccessibility. Yogurt samples...
5.
Viegas C, Araujo N, Carreira J, Pontes J, Macedo A, Vinhas M, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563203
Chronic inflammation is a major driver of chronic inflammatory diseases (CIDs), with a tremendous impact worldwide. Besides its function as a pathological calcification inhibitor, vitamin K-dependent protein Gla-rich protein (GRP)...
6.
Guerreiro F, Swedrowska M, Patel R, Florez-Fernandez N, Torres M, Rosa da Costa A, et al.
Int J Pharm . 2021 May; 604:120731. PMID: 34029661
Few medically-approved excipients are available for formulation strategies to endow microcarriers with improved performance in lung drug targeting. Konjac glucomannan (KGM) is a novel, biocompatible material, comprising mannose units potentially...
7.
Rodrigues S, Cunha L, Kollan J, Neumann P, Rosa da Costa A, Dailey L, et al.
Eur J Pharm Biopharm . 2021 Apr; 163:171-178. PMID: 33838263
Tuberculosis remains a leading cause of death, therapeutic failure being mainly due to non-compliance with prolonged treatments, often associated with severe side-effects. New therapeutic strategies are demanded and, considering that...
8.
Rosso A, Andretto V, Chevalier Y, Kryza D, Sidi-Boumedine J, Grenha A, et al.
J Control Release . 2021 Apr; 333:579-592. PMID: 33838210
In this work, nanocomposites that combine mucopenetrating and mucoadhesive properties in a single system are proposed as innovative strategy to increase drug residence time in the intestine following oral administration....
9.
Florez-Fernandez N, Alvarez-Vinas M, Guerreiro F, Torres M, Grenha A, Dominguez H
Mar Drugs . 2020 Jul; 18(7). PMID: 32605020
A green extraction process using only water was proposed for the simultaneous extraction of alginate and bioactive compounds from . Operation was carried out during non-isothermal heating up to maximal...
10.
Rodrigues S, Cunha L, Rico J, Rosa da Costa A, Almeida A, Faleiro M, et al.
Drug Deliv Transl Res . 2020 Jun; 10(6):1675-1687. PMID: 32562253
Macrophages have unique surface receptors that might recognize preferentially several moieties present on the surface of infecting organisms, including in the bacterial cell wall. Benefiting from a similar composition regarding...