Ana D Lopez
Overview
Explore the profile of Ana D Lopez including associated specialties, affiliations and a list of published articles.
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10
Citations
412
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Recent Articles
1.
Fogel G, Kai Z, Zargar S, Hinton A, Jones G, Wong A, et al.
Gene
. 2015 Aug;
574(2):359-70.
PMID: 26297998
MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as critical regulators of human embryonic stem cell (hESC) pluripotency and differentiation. Despite the wealth of information about the role individual...
2.
Lopez A, Kayali A, Hayek A, King C
J Vis Exp
. 2014 Jun;
(87).
PMID: 24895054
For almost 30 years, scientists have demonstrated that human fetal ICCs transplanted under the kidney capsule of nude mice matured into functioning endocrine cells, as evidenced by a significant increase...
3.
Hinton A, Hunter S, Afrikanova I, Jones G, Lopez A, Fogel G, et al.
Stem Cells
. 2014 May;
32(9):2360-72.
PMID: 24805944
MicroRNAs (miRNAs) are noncoding, regulatory RNAs expressed dynamically during differentiation of human embryonic stem cells (hESCs) into defined lineages. Mapping developmental expression of miRNAs during transition from pluripotency to definitive...
4.
Kayali A, Lopez A, Hao E, Hinton A, Hayek A, King C
PLoS One
. 2012 Jul;
7(6):e38721.
PMID: 22761699
The chemokine receptor CXCR4 and ligand SDF-1α are expressed in fetal and adult mouse islets. Neutralization of CXCR4 has previously been shown to diminish ductal cell proliferation and increase apoptosis...
5.
King C, Beattie G, Lopez A, Hayek A
Regen Med
. 2008 Mar;
3(2):175-80.
PMID: 18307401
Purpose: The purpose of these studies was twofold: to reduce the level of nonhuman, potentially immunogenic sialic acid N-glycolylneuraminic acid (Neu5Gc) in human embryonic stem cells (hESCs) through culture of...
6.
Kayali A, Flores L, Lopez A, Kutlu B, Baetge E, Kitamura R, et al.
Diabetes
. 2007 Mar;
56(3):703-8.
PMID: 17327439
Limited organ availability is an obstacle to the widespread use of islet transplantation in type 1 diabetic patients. To address this problem, many studies have explored methods for expanding functional...
7.
Beattie G, Lopez A, Bucay N, Hinton A, Firpo M, King C, et al.
Stem Cells
. 2005 Mar;
23(4):489-95.
PMID: 15790770
To date, all human embryonic stem cells (hESCs) available for research require unidentified soluble factors secreted from feeder layers to maintain the undifferentiated state and pluripotency. Activation of STAT3 by...
8.
Humphrey R, Beattie G, Lopez A, Bucay N, King C, Firpo M, et al.
Stem Cells
. 2004 Jul;
22(4):522-30.
PMID: 15277698
The preservation of "stemness" in mouse embryonic stem (mES) cells is maintained through a signal transduction pathway that requires the gp130 receptor, the interleukin-6 (IL-6) family of cytokines, and the...
9.
Beattie G, Montgomery A, Lopez A, Hao E, Perez B, Just M, et al.
Diabetes
. 2002 Nov;
51(12):3435-9.
PMID: 12453897
Human islet expansion in monolayer culture leads to loss of function and senescence. By maintaining the 3-D configuration of islets in fibrin gels, it is feasible to expand beta-cells in...
10.
Movassat J, Beattie G, Lopez A, Hayek A
J Clin Endocrinol Metab
. 2002 Oct;
87(10):4775-81.
PMID: 12364473
In addition to stimulating insulin secretion, glucagon-like peptide and its long-acting analog exendin 4 have been reported to increase beta-cell mass by both differentiation/neogenesis of precursor cells and enhanced replication...