Ana Cristina Silva Pinto
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Explore the profile of Ana Cristina Silva Pinto including associated specialties, affiliations and a list of published articles.
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12
Citations
77
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Recent Articles
1.
Araujo A, Silva Pinto A, de Castro Lobo C, Figueiredo M, Gualandro S, Olalla Saad S, et al.
Hemoglobin
. 2024 Apr;
48(4):218-230.
PMID: 38663998
Sickle cell disease (SCD) comprises inherited red blood cell disorders due to a mutation in the β-globin gene (c20A > T, pGlu6Val) and is characterized by the presence of abnormal...
2.
Lobo C, Araujo A, Antunes A, Silva Pinto A, Godinho A, Pires C, et al.
Hematol Transfus Cell Ther
. 2024 Feb;
46(1):67-71.
PMID: 38326179
To date, hydroxyurea is the only effective and safe drug that significantly reduces morbidity and mortality of individuals with Sickle cell disease. Twenty years of real-life experience has demonstrated that...
3.
Araujo A, Silva Pinto A, de Castro Lobo C, Figueiredo M, Gualandro S, Olalla Saad S, et al.
Hemoglobin
. 2023 Jun;
47(2):71-79.
PMID: 37309063
The polymerization of hemoglobin under deoxygenation is the main pathophysiological event in sickle cell diseases, described more than 70 years ago. The last two decades have seen a major increase...
4.
Azevedo J, de Mello Costa T, Lima K, Trovati Maciel T, Bonini Palma P, Darrigo-Junior L, et al.
Front Immunol
. 2021 Dec;
12:774442.
PMID: 34956203
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only currently available curative treatment for sickle cell disease (SCD). However, the effects of HSCT on SCD pathophysiology are poorly elucidated. Here,...
5.
Tozatto-Maio K, Girot R, Ly I, Silva Pinto A, Rocha V, Fernandes F, et al.
Front Immunol
. 2020 Oct;
11:2041.
PMID: 33013863
Sickle cell disease (SCD), the most common monogenic disease worldwide, is marked by a phenotypic variability that is, to date, only partially understood. Because inflammation plays a major role in...
6.
Tozatto-Maio K, Torres M, Degaide N, Cardoso J, Volt F, Silva Pinto A, et al.
Biol Blood Marrow Transplant
. 2020 Jul;
26(11):2034-2039.
PMID: 32712327
Sickle cell disease (SCD) is the most common inherited hemoglobinopathy. Hematopoietic stem cell transplantation (HCT) is the sole curative therapy for SCD, but few patients will have a matched sibling...
7.
Bezerra R, Santos E, Silveira R, Silva Pinto A, Covas D, Kashima S, et al.
Transfus Apher Sci
. 2019 Dec;
59(2):102697.
PMID: 31859221
Due to the high number of transfusions which patients with hereditary hemoglobinopathies (thalassemia, sickle cell disease) receive, they represent high risk of acquiring parenterally transmitted infectious diseases. In this respect,...
8.
Lizarralde Iragorri M, El Hoss S, Brousse V, Lefevre S, Dussiot M, Xu T, et al.
Lab Chip
. 2018 Sep;
18(19):2975-2984.
PMID: 30168832
The human red blood cell is a biconcave disc of 6-8 × 2 μm that is highly elastic. This capacity to deform enables it to stretch while circulating through narrow...
9.
de Castro Lobo C, Cancado R, Leite A, Dos Anjos A, Silva Pinto A, Matta A, et al.
Rev Bras Hematol Hemoter
. 2013 Jan;
33(1):43-8.
PMID: 23284243
Background: Sickle cell disease is the most common monogenic hereditary disease in Brazil. Although strokes are one of the main causes of morbidity and mortality in these patients, the use...
10.
Lima E, Silva Pinto A, Nogueira K, Rocha E Silva L, Oliveira de Almeida P, de Vasconcellos M, et al.
Molecules
. 2012 Dec;
18(1):178-89.
PMID: 23262447
4-nerolidylcatechol (4-NC) is an unstable natural product that exhibits important antioxidant, anti-inflammatory and other properties. It is readily obtainable on a multi-gram scale through straightforward solvent extraction of the roots...