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Ana Catarina R G Fonseca

Explore the profile of Ana Catarina R G Fonseca including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 234
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Recent Articles
1.
Silva A, Pereira C, Fonseca A, Pinto-do-O P, Nascimento D
Front Cell Dev Biol . 2021 Jan; 8:621644. PMID: 33511134
The extracellular matrix (ECM) is an essential component of the heart that imparts fundamental cellular processes during organ development and homeostasis. Most cardiovascular diseases involve severe remodeling of the ECM,...
2.
Miranda-Silva D, Rodrigues P, Alves E, Rizo D, Fonseca A, Lima T, et al.
Circ Heart Fail . 2020 Nov; 13(11):e006170. PMID: 33176457
Background: Often, pressure overload-induced myocardial remodeling does not undergo complete reverse remodeling after decreasing afterload. Recently, mitochondrial abnormalities and oxidative stress have been successively implicated in the pathogenesis of several...
3.
Fonseca A, Carvalho E, Eriksson J, Pereira M
Mol Cell Biochem . 2018 Jan; 445(1-2):157-168. PMID: 29380240
Calcineurin inhibitors are used in immunosuppressive therapy applied after transplantation, but they are associated with major metabolic side effects including the development of new onset diabetes. Previously, we have shown...
4.
Fonseca A, Moreira P, Oliveira C, Cardoso S, Pinton P, Pereira C
Mol Neurobiol . 2014 May; 51(2):610-22. PMID: 24833600
In Alzheimer's disease, the accumulation of amyloid-beta (Aβ) in the brain occurs in the parenchyma and cerebrovasculature. Several evidences support that the neuronal demise is potentiated by vascular alterations in...
5.
Fonseca A, Ferreiro E, Oliveira C, Cardoso S, Pereira C
Biochim Biophys Acta . 2013 Sep; 1832(12):2191-203. PMID: 23994613
Neurovascular dysfunction arising from endothelial cell damage is an early pathogenic event that contributes to the neurodegenerative process occurring in Alzheimer's disease (AD). Since the mechanisms underlying endothelial dysfunction are...
6.
Fonseca A, Resende R, Oliveira C, Pereira C
Exp Neurol . 2009 Sep; 223(2):282-93. PMID: 19782682
Alzheimer's disease (AD) is the principal cause of dementia in older people, and accumulation of amyloid-beta (Abeta) peptide is a crucial event in AD pathogenesis. Despite opposite results found in...
7.
Fonseca A, Proenca T, Resende R, Oliveira C, Pereira C
J Alzheimers Dis . 2009 Apr; 17(3):503-17. PMID: 19363255
Statins, used as cholesterol-lowering drugs, were reported to reduce the progression of Alzheimer's disease (AD). However, the molecular mechanisms underlying these findings remain to be clarified and it is not...