Ana C Lima
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Explore the profile of Ana C Lima including associated specialties, affiliations and a list of published articles.
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23
Citations
182
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Recent Articles
1.
Yang R, Celino-Brady F, Dunleavy J, Vigh-Conrad K, Atkins G, Hvasta R, et al.
Biol Reprod
. 2025 Feb;
PMID: 39961022
Analysis of testis histology is fundamental to the study of male fertility, but it is a slow task with a high skill threshold. Here, we describe new neural network models...
2.
Lima A, Okhovat M, Stendahl A, Yang R, VanCampen J, Nevonen K, et al.
Biol Reprod
. 2025 Feb;
PMID: 39903672
Spermatogenesis is a complex process that can be disrupted by genetic and epigenetic changes, potentially leading to male infertility. Recent research has rapidly increased the number of protein coding mutations...
3.
Silva C, Casanova M, Ferreirinha P, da Silva Morais A, Osorio H, Lima A, et al.
Life Sci
. 2025 Jan;
362():123366.
PMID: 39761741
Aims: The development and selection of T cells occur within the thymus. This organ involutes throughout life, compromising the generation of T cells and, consequently, the efficacy of the immune...
4.
Lima A, Okhovat M, Stendahl A, VanCampen J, Nevonen K, Herrera J, et al.
bioRxiv
. 2024 Jul;
PMID: 39026739
Spermatogenesis is a complex process that can be disrupted by genetic and epigenetic changes, potentially leading to male infertility. Recent research has rapidly increased the number of protein coding mutations...
5.
Mahyari E, Vigh-Conrad K, Daube C, Lima A, Guo J, Carrell D, et al.
Andrology
. 2024 Apr;
PMID: 38577799
Background: Single-cell RNA-seq (scRNA-Seq) has been widely adopted to study gene expression of the human testis. Several datasets of scRNA-Seq from human testis have been generated from different groups processed...
6.
Okhovat M, VanCampen J, Nevonen K, Harshman L, Li W, Layman C, et al.
Nat Commun
. 2023 Dec;
14(1):8111.
PMID: 38062027
Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely unknown....
7.
Stendahl A, Sanghvi R, Peterson S, Ray K, Lima A, Rahbari R, et al.
Genome Res
. 2023 Nov;
33(12):2053-2059.
PMID: 37984997
As part of an ongoing genome sequencing project at the Oregon National Primate Research Center, we identified a rhesus macaque with a rare homozygous frameshift mutation in the gene methyl-CpG...
8.
Okhovat M, VanCampen J, Lima A, Nevonen K, Layman C, Ward S, et al.
bioRxiv
. 2023 Mar;
PMID: 36945527
Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely unknown....
9.
Yang R, Stendahl A, Vigh-Conrad K, Held M, Lima A, Conrad D
Bioinformatics
. 2022 Oct;
38(23):5288-5298.
PMID: 36214638
Motivation: The mammalian testis is a complex organ with a cellular composition that changes smoothly and cyclically in normal adults. While testis histology is already an invaluable tool for identifying...
10.
Vasconcelos F, Lima A, Bonani W, Silva C, Reis R, Motta A, et al.
Biomater Adv
. 2022 May;
134:112585.
PMID: 35525755
Inflammatory arthritic diseases are characterized by a persistent inflammation of the synovial tissues where tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) pro-inflammatory cytokines are over-expressed, leading to progressive musculoskeletal...