Ana Belchior
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Explore the profile of Ana Belchior including associated specialties, affiliations and a list of published articles.
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14
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61
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Recent Articles
1.
Belchior A, Alves B, Mendes E, Megre F, Alves L, Santos P, et al.
EJNMMI Res
. 2025 Feb;
15(1):13.
PMID: 39982528
Background: Protons, which are considered low-LET (Linear Energy Transfer) radiation, have an average RBE (relative biological effectiveness) of 1.1, with a range from 0.7 to 1.6. Thus, increasing biological effectiveness...
2.
Oliveira M, Campello M, Gano L, Raposinho P, Belchior A, Mendes E, et al.
ChemMedChem
. 2024 Sep;
19(24):e202400438.
PMID: 39302068
We herein describe the radiosynthesis of a I-labeled acridine orange derivative ([I]-C), acting as a G-quadruplex binder, and its biological evaluation in cervical cancer models, aiming to enlighten its potential...
3.
Palma E, Ichedef C, Fernandes C, Belchior A, Raposinho P, Gano L, et al.
Chemistry
. 2024 Feb;
30(22):e202400285.
PMID: 38386665
The main goal of this work was to elucidate the potential relevance of (radio)metal chelates of Tc and Re targeting G-quadruplex structures for the design of new tools for cancer...
4.
Belchior A, Canhoto J, Giesen U, Langner F, Rabus H, Schulte R
Life (Basel)
. 2024 Jan;
14(1).
PMID: 38255757
In the original publication [...].
5.
Belchior A, Canhoto J, Giesen U, Langner F, Rabus H, Schulte R
Life (Basel)
. 2022 Dec;
12(12).
PMID: 36556405
In this work, the induction and repair of radiation-induced 53BP1 foci were studied in human umbilical vein endothelial cells irradiated at the PTB microbeam with protons and α-particles of different...
6.
Belchior A, Fernandes A, Lamotte M, Silva A, Seixas R, Silva A, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499256
Boron neutron capture therapy (BNCT) is a re-emerging technique for selectively killing tumor cells. Briefly, the mechanism can be described as follows: after the uptake of boron into cells, the...
7.
Fernandes C, Palma E, Silva F, Belchior A, Pinto C, Guerreiro J, et al.
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806239
Although Tc is not an ideal Auger electron (AE) emitter for Targeted Radionuclide Therapy (TRT) due to its relatively low Auger electron yield, it can be considered a readily available...
8.
Marques A, Belchior A, Silva F, Marques F, Campello M, Pinheiro T, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563666
For a while, gold nanoparticles (AuNPs) have been recognized as potential radiosensitizers in cancer radiation therapy, mainly due to their physical properties, making them appealing for medical applications. Nevertheless, the...
9.
Silva F, DOnofrio A, Mendes C, Pinto C, Marques A, Campello M, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35054798
Despite some progress, the overall survival of patients with glioblastoma (GBM) remains extremely poor. In this context, there is a pressing need to develop innovative therapy strategies for GBM, namely...
10.
Figueiredo D, Fernandes C, Silva F, Palma E, Raposinho P, Belchior A, et al.
Molecules
. 2021 Jan;
26(2).
PMID: 33467760
For effective Auger therapy of cancer, the Auger-electron emitters must be delivered to the tumor cells in close proximity to a radiosensitive cellular target. Nuclear DNA is considered the most...