Amrit Kumar Shrestha
Overview
Explore the profile of Amrit Kumar Shrestha including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
144
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Recent Articles
1.
Palit S, Shrestha A, Thapa S, Grimm S, Coarfa C, Theis F, et al.
Genes (Basel)
. 2024 Jun;
15(6).
PMID: 38927741
Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly affecting premature infants, with limited therapeutic options and increased long-term consequences. Adrenomedullin (), a proangiogenic peptide hormone, has been found to...
2.
Thapa S, Shankar N, Shrestha A, Civunigunta M, Gaikwad A, Shivanna B
Antioxidants (Basel)
. 2024 Jan;
13(1).
PMID: 38247502
Interrupted lung angiogenesis is a hallmark of bronchopulmonary dysplasia (BPD); however, druggable targets that can rescue this phenotype remain elusive. Thus, our investigation focused on amphiregulin (Areg), a growth factor...
3.
Shankar N, Thapa S, Shrestha A, Sarkar P, Gaber M, Barrios R, et al.
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978868
Inflammation causes bronchopulmonary dysplasia (BPD), a common lung disease of preterm infants. One reason this disease lacks specific therapies is the paucity of information on the mechanisms regulating inflammation in...
4.
Menon R, Thapa S, Shrestha A, Barrios R, Shivanna B
Antioxidants (Basel)
. 2022 Jun;
11(6).
PMID: 35740027
Bronchopulmonary dysplasia (BPD) is a morbid lung disease distinguished by lung alveolar and vascular simplification. Hyperoxia, an important BPD causative factor, increases extracellular signal-regulated kinases (ERK)-1/2 expression, whereas decreased lung...
5.
Shrestha A, Menon R, El-Saie A, Barrios R, Reynolds C, Shivanna B
Am J Physiol Lung Cell Mol Physiol
. 2020 Sep;
319(6):L981-L996.
PMID: 32901520
Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is a chronic infantile lung disease that lacks curative therapies. Infants with BPD-associated PH are often exposed to hyperoxia and additional insults such as...
6.
Menon R, Shrestha A, Barrios R, Reynolds C, Shivanna B
Int J Mol Sci
. 2020 Apr;
21(7).
PMID: 32244398
Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is a significant lung morbidity of infants, and disrupted lung angiogenesis is a hallmark of this disease. We observed that extracellular signal-regulated kinases (ERK)...
7.
Menon R, Shrestha A, Reynolds C, Barrios R, Caron K, Shivanna B
Am J Pathol
. 2020 Feb;
190(3):711-722.
PMID: 32093901
Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is an infantile lung disease characterized by aberrant angiogenesis and impaired resolution of lung injury. Adrenomedullin (AM) signals through calcitonin receptor-like receptor and receptor...
8.
Shrestha A, Bettini M, Menon R, Gopal V, Huang S, Edwards D, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Oct;
316(1):L229-L244.
PMID: 30307313
Bronchopulmonary dysplasia (BPD) is a chronic lung disease of infants that is characterized by interrupted lung development. Postnatal sepsis causes BPD, yet the contributory mechanisms are unclear. To address this...
9.
Shrestha A, Menon R, Shivanna B
Biochem Biophys Res Commun
. 2018 Aug;
503(3):2009-2014.
PMID: 30077371
Hyperoxia-induced oxidative stress contributes to the pathogenesis of bronchopulmonary dysplasia (BPD), the most common respiratory morbidity of preterm infants. Importantly, the disease lack specific therapies and is associated with long-term...
10.
Shrestha A, Gopal V, Menon R, Hagan J, Huang S, Shivanna B
Am J Physiol Lung Cell Mol Physiol
. 2018 Jul;
315(5):L734-L741.
PMID: 30047283
Bronchopulmonary dysplasia (BPD), the most common chronic lung disease in infants, is associated with long-term morbidities, including pulmonary hypertension (PH). Importantly, hyperoxia causes BPD and PH; however, the underlying mechanisms...