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Amogelang R Raphenya

Explore the profile of Amogelang R Raphenya including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 3515
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Recent Articles
1.
Hackenberger D, Imtiaz H, Raphenya A, Alcock B, Poinar H, Wright G, et al.
Appl Environ Microbiol . 2025 Feb; :e0187624. PMID: 40019273
Better interrogation of antimicrobial resistance requires new approaches to detect the associated genes in metagenomic samples. Targeted enrichment is an ideal method for their sequencing and characterization. However, no open-source,...
2.
Nasir J, Maguire F, Smith K, Panousis E, Baker S, Aftanas P, et al.
NAR Genom Bioinform . 2024 Dec; 6(4):lqae176. PMID: 39703420
The incorporation of sequencing technologies in frontline and public health healthcare settings was vital in developing virus surveillance programs during the Coronavirus Disease 2019 (COVID-19) pandemic caused by transmission of...
3.
Lu D, Kalantar K, Chu V, Glascock A, Guerrero E, Bernick N, et al.
bioRxiv . 2024 Apr; PMID: 38645206
Antimicrobial resistant (AMR) pathogens represent urgent threats to human health, and their surveillance is of paramount importance. Metagenomic next generation sequencing (mNGS) has revolutionized such efforts, but remains challenging due...
4.
Timme R, Karsch-Mizrachi I, Waheed Z, Arita M, MacCannell D, Maguire F, et al.
Microb Genom . 2023 Dec; 9(12). PMID: 38085797
Fast, efficient public health actions require well-organized and coordinated systems that can supply timely and accurate knowledge. Public databases of pathogen genomic data, such as the International Nucleotide Sequence Database...
5.
Day E, Townsend L, Rehal S, Batchuluun B, Wang D, Morrow M, et al.
iScience . 2023 Nov; 26(11):108269. PMID: 38026185
Atherosclerotic cardiovascular disease is characterized by both chronic low-grade inflammation and dyslipidemia. The AMP-activated protein kinase (AMPK) inhibits cholesterol synthesis and dampens inflammation but whether pharmacological activation reduces atherosclerosis is...
6.
Smith K, Alcock B, French S, Farha M, Raphenya A, Brown E, et al.
Microbiol Spectr . 2023 Nov; 11(6):e0274423. PMID: 37971258
While increasing rates of antimicrobial resistance undermine our current arsenal of antibiotics, resistance-modifying agents (RMAs) hold promise to extend the lifetime of these important molecules. We here provide a standardized...
7.
Alcock B, Huynh W, Chalil R, Smith K, Raphenya A, Wlodarski M, et al.
Nucleic Acids Res . 2022 Oct; 51(D1):D690-D699. PMID: 36263822
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and...
8.
Sanderson H, Gray K, Manuele A, Maguire F, Khan A, Liu C, et al.
Microb Genom . 2022 Sep; 8(9). PMID: 36129737
is a ubiquitous opportunistic pathogen that is exhibiting increasing levels of antimicrobial resistance (AMR). Many of the genes that confer resistance and pathogenic functions are localized on mobile genetic elements...
9.
Guitor A, Yousuf E, Raphenya A, Hutton E, Morrison K, McArthur A, et al.
Microbiome . 2022 Aug; 10(1):136. PMID: 36008821
Background: Probiotic use in preterm infants can mitigate the impact of antibiotic exposure and reduce rates of certain illnesses; however, the benefit on the gut resistome, the collection of antibiotic...
10.
Raphenya A, Robertson J, Jamin C, de Oliveira Martins L, Maguire F, McArthur A, et al.
Sci Data . 2022 Jun; 9(1):341. PMID: 35705638
Whole genome sequencing (WGS) is a key tool in identifying and characterising disease-associated bacteria across clinical, agricultural, and environmental contexts. One increasingly common use of genomic and metagenomic sequencing is...