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Ammar J Alsheikh

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Articles 14
Citations 169
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Recent Articles
1.
Khedr S, Dissanayake L, Alsheikh A, Zietara A, Spires D, Kerketta R, et al.
JCI Insight . 2024 Nov; 10(1. PMID: 39589791
Diabetic kidney disease (DKD) is the leading cause of chronic renal pathology. Understanding the molecular underpinnings of DKD is critical to designing tailored therapeutic approaches. Here, we focused on sex...
2.
Lenarczyk M, Alsheikh A, Cohen E, Schaue D, Kronenberg A, Geurts A, et al.
Toxics . 2023 Feb; 11(2). PMID: 36851074
In the original publication [...].
3.
Lenarczyk M, Alsheikh A, Cohen E, Schaue D, Kronenberg A, Geurts A, et al.
Toxics . 2022 Dec; 10(12). PMID: 36548630
Heart disease is a significant adverse event caused by radiotherapy for some cancers. Identifying the origins of radiogenic heart disease will allow therapies to be developed. Previous studies showed non-targeted...
4.
Alsheikh A, Wollenhaupt S, King E, Reeb J, Ghosh S, Stolzenburg L, et al.
BMC Med Genomics . 2022 Apr; 15(1):74. PMID: 35365203
Background: The remarkable growth of genome-wide association studies (GWAS) has created a critical need to experimentally validate the disease-associated variants, 90% of which involve non-coding variants. Methods: To determine how...
5.
Dasinger J, Abais-Battad J, Bukowy J, Lund H, Alsheikh A, Fehrenbach D, et al.
Pregnancy Hypertens . 2021 May; 24:126-134. PMID: 33971615
Preeclampsia (PE) is a disorder of pregnancy, which is categorized by hypertension and proteinuria or signs of end-organ damage. Though PE is the leading cause of maternal and fetal morbidity...
6.
Abais-Battad J, Saravia F, Lund H, Dasinger J, Fehrenbach D, Alsheikh A, et al.
Acta Physiol (Oxf) . 2021 Apr; 232(4):e13662. PMID: 33866692
Aim: Our previous studies have demonstrated the importance of dietary factors in the determination of hypertension in Dahl salt-sensitive (SS) rats. Since the gut microbiota has been implicated in chronic...
7.
Shimada S, Abais-Battad J, Alsheikh A, Yang C, Stumpf M, Kurth T, et al.
Hypertension . 2020 Aug; 76(3):849-858. PMID: 32755400
The present study examined the extent to which leukocyte infiltration into the kidneys in Ang II (angiotensin II)-induced hypertension is determined by elevation of renal perfusion pressure (RPP). Male Sprague-Dawley...
8.
Alsheikh A, Dasinger J, Abais-Battad J, Fehrenbach D, Yang C, Cowley Jr A, et al.
Am J Physiol Renal Physiol . 2020 Mar; 318(4):F982-F993. PMID: 32150444
Studies examining mechanisms of Dahl salt-sensitive (SS) hypertension have implicated the infiltration of leukocytes in the kidneys, which contribute to renal disease and elevated blood pressure. However, the signaling pathways...
9.
Dasinger J, Alsheikh A, Abais-Battad J, Pan X, Fehrenbach D, Lund H, et al.
Hypertension . 2019 Dec; 75(2):372-382. PMID: 31838911
The SS (Dahl salt sensitive) rat is an established model of hypertension and renal damage that is accompanied with immune system activation in response to a high-salt diet. Investigations into...
10.
Abais-Battad J, Alsheikh A, Pan X, Fehrenbach D, Dasinger J, Lund H, et al.
Hypertension . 2019 Sep; 74(4):854-863. PMID: 31476910
The Dahl salt-sensitive (SS) rat is an established model of SS hypertension and renal damage. In addition to salt, other dietary components were shown to be important determinants of hypertension...