Amit Pathak
Overview
Explore the profile of Amit Pathak including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
1088
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Recent Articles
11.
Lin W, Pathak A
bioRxiv
. 2023 Apr;
PMID: 37090663
Epithelial cell collectives migrate through tissue interfaces and crevices to orchestrate processes of development, tumor invasion, and wound healing. Naturally, traversal of cell collective through confining environments involves crowding due...
12.
Walter C, Mathur J, Pathak A
Cell Rep
. 2023 Apr;
42(4):112362.
PMID: 37027304
Adherent cells migrate on layered tissue interfaces to drive morphogenesis, wound healing, and tumor invasion. Although stiffer surfaces are known to enhance cell migration, it remains unclear whether cells sense...
13.
Zmuda H, Pathak A
bioRxiv
. 2023 Mar;
PMID: 36865200
Summary: Authors show proinflammatory macrophages on soft matrices enable epithelial cells to form multicellular clusters. This phenomenon is disabled on stiff matrices due to increased stability of focal adhesions. Inflammatory...
14.
Krull C, Li H, Pathak A
Elife
. 2023 Feb;
12.
PMID: 36805020
Dynamic nucleocytoplasmic transport of E-M factors regulates cellular E-M states; yet, it remains unknown how simultaneously trapping these factors affects epithelia at the macroscale. To explore this question, we performed...
15.
Almeida J, Mathur J, Lee Y, Sarker B, Pathak A
Mol Biol Cell
. 2023 Jan;
34(6):ar54.
PMID: 36696158
Cells sense and migrate across mechanically dissimilar environments throughout development and disease progression. However, it remains unclear whether mechanical memory of past environments empowers cells to navigate new, three-dimensional extracellular...
16.
Hwang P, Mathur J, Cao Y, Almeida J, Ye J, Morikis V, et al.
Dev Cell
. 2023 Jan;
58(1):34-50.e9.
PMID: 36626870
Carcinoma dissemination can occur when heterogeneous tumor and tumor-stromal cell clusters migrate together via collective migration. Cells at the front lead and direct collective migration, yet how these leader cells...
17.
Pandey A, Srivastav S, Vats A, Pathak A, Singh K
Spectrochim Acta A Mol Biomol Spectrosc
. 2023 Jan;
290:122299.
PMID: 36608520
The rotational line survey by ALMA (Atacama Large Millimeter/submillimeter Array) recently revealed the presence of i-CHCN (i-PrCN) and n-CHCN (n-PrCN) in 3-mm atmospheric window between 84 to 111 GHz towards...
18.
Flick Jaecker F, Almeida J, Krull C, Pathak A
Mol Biol Cell
. 2022 Jul;
33(11):br19.
PMID: 35830599
Cancer cells are known to have larger nucleoli, consistent with their higher transcriptional and translational demands. Meanwhile, on stiff extracellular matrix, normal epithelial cells can exhibit genomic and proteomic mechanoactivation...
19.
Price C, Mathur J, Boerckel J, Pathak A, Shenoy V
Biophys J
. 2021 Oct;
120(22):5074-5089.
PMID: 34627766
Mechanotransduction describes activation of gene expression by changes in the cell's physical microenvironment. Recent experiments show that mechanotransduction can lead to long-term "mechanical memory," in which cells cultured on stiff...
20.
Sarker B, Walter C, Pathak A
ACS Biomater Sci Eng
. 2021 Jan;
4(7):2340-2349.
PMID: 33435100
Microcontact printing of extracellular matrix (ECM) proteins in defined regions of a substrate allows spatial control over cell attachment and enables the study of cellular response to irregular ECM geometries....