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Amit Meller

Explore the profile of Amit Meller including associated specialties, affiliations and a list of published articles. Areas
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Articles 77
Citations 3104
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Recent Articles
1.
Pal S, Huttner D, Verma N, Nemirovsky T, Ziv O, Sher N, et al.
ACS Nano . 2025 Mar; PMID: 40082088
Mitochondrial DNA (mtDNA) quantification is crucial in understanding mitochondrial dysfunction, which is linked to a variety of diseases, including cancer and neurodegenerative disorders. Traditional methods often rely on amplification-based techniques,...
2.
Ohayon S, Taib L, Verma N, Iarossi M, Bhattacharya I, Marom B, et al.
Adv Mater . 2024 Mar; 36(25):e2314319. PMID: 38461367
Emerging single-molecule protein sensing techniques are ushering in a transformative era in biomedical research. Nevertheless, challenges persist in realizing ultra-fast full-length protein sensing, including loss of molecular integrity due to...
3.
Soni N, Verma N, Talor N, Meller A
Nano Lett . 2023 May; 23(10):4609-4616. PMID: 37149783
Solid-state nanopores (ssNPs) are single-molecule sensors capable of label-free quantification of different biomolecules, which have become highly versatile with the introduction of different surface treatments. By modulating the surface charges...
4.
Ying Y, Hu Z, Zhang S, Qing Y, Fragasso A, Maglia G, et al.
Nat Nanotechnol . 2022 Sep; 17(11):1136-1146. PMID: 36163504
Inspired by the biological processes of molecular recognition and transportation across membranes, nanopore techniques have evolved in recent decades as ultrasensitive analytical tools for individual molecules. In particular, nanopore-based single-molecule...
5.
Soni N, Freundlich N, Ohayon S, Huttner D, Meller A
ACS Nano . 2022 Jul; 16(7):11405-11414. PMID: 35785960
The ability to routinely identify and quantify the complete proteome from single cells will greatly advance medicine and basic biology research. To meet this challenge of single-cell proteomics, single-molecule technologies...
6.
van Kooten X, Rozevsky Y, Marom Y, Ben Sadeh E, Meller A
Nanoscale . 2022 Mar; 14(13):4977-4986. PMID: 35258059
The majority of RNA based COVID-19 diagnostics employ enzymatic amplification to achieve high sensitivity, but this relies on arbitrary thresholding, which complicates the comparison of test results and may lead...
7.
Meller A
Mol Cell . 2022 Jan; 82(2):237-238. PMID: 35063092
Novel techniques for single-protein molecule sequencing are rapidly becoming the focus of contemporary biomedical research. Here, Brinkerhoff et al. (2021) report a significant progress in nanopore-based rereading of DNA-peptide conjugates.
8.
Nasser M, Meller A
iScience . 2022 Jan; 25(1):103554. PMID: 34977508
Single biomolecule sensing often requires the quantification of multiple fluorescent species. Here, we theoretically and experimentally use time-resolved fluorescence via Time Correlated Single Photon Counting (TCSPC) to accurately quantify fluorescent...
9.
Joo C, Meller A
iScience . 2021 Oct; 24(10):103161. PMID: 34693220
No abstract available.
10.
Zvuloni E, Zrehen A, Gilboa T, Meller A
ACS Nano . 2021 Jul; 15(7):12189-12200. PMID: 34219449
Nanopores are single-molecule sensors capable of detecting and quantifying a broad range of unlabeled biomolecules including DNA and proteins. Nanopores' generic sensing principle has permitted the development of a vast...