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Amit Kokate

Explore the profile of Amit Kokate including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 40
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Recent Articles
1.
Goswami T, Kokate A, Jasti B, Li X
Arch Oral Biol . 2012 Nov; 58(5):545-51. PMID: 23123066
The objective of this work was to develop an in silico model to predict the sublingual permeability of a drug based on physicochemical descriptors of a molecule. Fourteen model drugs...
2.
Kokate A, Li X, Williams P, Singh P, Jasti B
Pharm Res . 2009 Feb; 26(5):1130-9. PMID: 19184372
Purpose: To develop and validate a computational model capable of predicting buccal permeability based on various structural and physicochemical descriptors. Methods: Apparent permeability coefficients (K(p)) of 15 different drugs across...
3.
Kokate A, Li X, Jasti B
AAPS PharmSciTech . 2008 Apr; 9(2):501-4. PMID: 18431653
No abstract available.
4.
Kokate A, Li X, Jasti B
J Pharm Biomed Anal . 2008 Feb; 47(1):190-4. PMID: 18242039
A simple, isocratic and sensitive high-performance liquid chromatographic (HPLC) method was developed and validated for the simultaneous analysis of marker compounds for the aqueous (atenolol) and lipoidal (lidocaine) pathways during...
5.
Kokate A, Li X, Singh P, Jasti B
J Pharm Sci . 2008 Jan; 97(10):4294-306. PMID: 18228580
The objective of this work was to delineate the contribution of thermodynamic activities of ionized and unionized species on buccal drug permeation. The flux and permeability of a model acidic...
6.
Kokate A, Li X, Jasti B
Invest New Drugs . 2006 Dec; 25(3):197-203. PMID: 17146731
Fenretinide is a synthetic retinoid with chemotherapeutic activity against various malignancies. Upon oral administration to animals, fenretinide was found to be incompletely absorbed and excreted primarily in feces. The purpose...