Amit Gruber
Overview
Explore the profile of Amit Gruber including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
199
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Recent Articles
1.
Haim I, Gruber A, Kazma N, Bashai C, Lichtig Kinsbruner H, Caspi O
Circ Heart Fail
. 2025 Jan;
e011690.
PMID: 39873109
Background: The therapeutic armamentarium for heart failure with preserved ejection fraction (HFpEF) remains notably constrained. A factor contributing to this problem could be the scarcity of in vitro models for...
2.
Abbo A, Gruber A, Volis I, Aronson D, Caspi O
JACC Heart Fail
. 2024 Dec;
12(12):2125-2126.
PMID: 39632014
No abstract available.
3.
Abbo A, Gruber A, Volis I, Aronson D, Girerd N, Kristensen S, et al.
JACC Heart Fail
. 2024 May;
12(8):1396-1405.
PMID: 38739124
Background: Limited evidence exists regarding efficacy and safety of diuretic regimens in ambulatory, congestion-refractory, chronic heart failure (CHF) patients. Objectives: The authors sought to compare the potency and safety of...
4.
Adir O, Albalak M, Abel R, Weiss L, Chen G, Gruber A, et al.
Nat Commun
. 2022 Apr;
13(1):2328.
PMID: 35484097
Development of regulated cellular processes and signaling methods in synthetic cells is essential for their integration with living materials. Light is an attractive tool to achieve this, but the limited...
5.
Gruber A, Edri O, Glatstein S, Goldfracht I, Huber I, Arbel G, et al.
J Am Heart Assoc
. 2022 Feb;
11(4):e021615.
PMID: 35112880
Background Optogenetics, using light-sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high-resolution optogenetic approaches to modulate electrical activity in 2- and 3-dimensional...
6.
Gruber A, Edri O, Huber I, Arbel G, Gepstein A, Shiti A, et al.
JCI Insight
. 2021 Jun;
6(11).
PMID: 34100384
Abnormal action potential (AP) properties, as occurs in long or short QT syndromes (LQTS and SQTS, respectively), can cause life-threatening arrhythmias. Optogenetics strategies, utilizing light-sensitive proteins, have emerged as experimental...
7.
Gruber A, Ghiringhelli M, Edri O, Abboud Y, Shiti A, Shaheen N, et al.
Acad Med
. 2021 Mar;
96(7):1005-1009.
PMID: 33788792
Problem: The COVID-19 pandemic has challenged health care systems in an unprecedented way by imposing new demands on health care resources and scientific knowledge. There has also been an exceedingly...
8.
Goldfracht I, Protze S, Shiti A, Setter N, Gruber A, Shaheen N, et al.
Nat Commun
. 2020 Jan;
11(1):75.
PMID: 31911598
The functions of the heart are achieved through coordination of different cardiac cell subtypes (e.g., ventricular, atrial, conduction-tissue cardiomyocytes). Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) offer unique opportunities for cardiac...
9.
Shaheen N, Shiti A, Huber I, Shinnawi R, Arbel G, Gepstein A, et al.
Stem Cell Reports
. 2018 May;
10(6):1879-1894.
PMID: 29754959
Fulfilling the potential of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes for studying conduction and arrhythmogenesis requires development of multicellular models and methods for long-term repeated tissue phenotyping. We generated...
10.
Gruber A, Edri O, Gepstein L
Europace
. 2018 Jan;
20(12):1910-1918.
PMID: 29315402
The emerging technology of optogenetics uses optical and genetic means to monitor and modulate the electrophysiological properties of excitable tissues. While transforming the field of neuroscience, the technology has recently...