Amit Fischer
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Explore the profile of Amit Fischer including associated specialties, affiliations and a list of published articles.
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12
Citations
68
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Recent Articles
1.
Ghosheh M, Ehrlich A, Fischer A, Pasitka L, Cohen M, Nahmias Y
Nat Commun
. 2024 Dec;
15(1):10767.
PMID: 39737916
The escalating global demand for meat products has intensified ecological concerns, underscoring the need for sustainable meat alternatives. Although current methods effectively imitate ground meat, mimicking whole cuts, which constitute...
2.
Fischer A, Ehrlich A, Plotkin Y, Ouyang Y, Asulin K, Konstantinos I, et al.
Angew Chem Int Ed Engl
. 2023 Sep;
62(43):e202311590.
PMID: 37675854
The combination of gene therapy and immunotherapy concepts, along recent advances in DNA nanotechnology, have the potential to provide important tools for cancer therapies. We present the development of stimuli-responsive...
3.
Ghosheh M, Ehrlich A, Ioannidis K, Ayyash M, Goldfracht I, Cohen M, et al.
Nat Biomed Eng
. 2023 Aug;
7(11):1493-1513.
PMID: 37550423
The study of cardiac physiology is hindered by physiological differences between humans and small-animal models. Here we report the generation of multi-chambered self-paced vascularized human cardiac organoids formed under anisotropic...
4.
Fischer A, Zhang P, Ouyang Y, Sohn Y, Karmi O, Nechushtai R, et al.
Small
. 2022 Nov;
18(52):e2204108.
PMID: 36351764
The assembly of adenosine triphosphate (ATP)-responsive and miRNA-responsive DNA tetrahedra-functionalized carboxymethyl cellulose hydrogel microcapsules is presented. The microcapsules are loaded with the doxorubicin-dextran drug or with CdSe/ZnS quantum dots as...
5.
Ioannidis K, Cohen A, Ghosheh M, Ehrlich A, Fischer A, Cohen M, et al.
Lab Chip
. 2022 Oct;
22(23):4469-4480.
PMID: 36281785
Aminoglycosides are an important class of antibiotics that play a critical role in the treatment of life-threatening infections, but their use is limited by their toxicity. In fact, gentamicin causes...
6.
Zhang P, Fischer A, Ouyang Y, Sohn Y, Nechushtai R, Zhang J, et al.
Chem Sci
. 2022 Oct;
13(35):10555-10565.
PMID: 36277654
Topological barriers control in nature the transcription machinery, thereby perturbing gene expression. Here we introduce synthetically designed DNA templates that include built-in topological barriers for switchable, triggered-controlled transcription of RNA...
7.
Zhang P, Fischer A, Ouyang Y, Wang J, Sohn Y, Karmi O, et al.
Chem Sci
. 2022 Jul;
13(25):7437-7448.
PMID: 35872834
Biomolecule-loaded nucleic acid-functionalized carboxymethyl cellulose hydrogel-stabilized microcapsules (diameter 2 μm) are introduced as cell-like containments. The microcapsules are loaded with two DNA tetrahedra, T and T, functionalized with guanosine-rich G-quadruplex...
8.
Zhang P, Fischer A, Ouyang Y, Wang J, Sohn Y, Nechushtai R, et al.
Chem Sci
. 2021 Dec;
12(43):14473-14483.
PMID: 34880998
UiO-66 metal-organic framework nanoparticles (NMOFs) gated by aptamer-functionalized DNA tetrahedra provide superior biomarker-responsive hybrid nano-carriers for biomedical applications. Hybrid nano-carriers consisting of ATP-aptamer or VEGF-aptamer functionalized tetrahedra-gated NMOFs are loaded...
9.
Wang C, Fischer A, Ehrlich A, Nahmias Y, Willner I
Chem Sci
. 2021 Jun;
11(17):4516-4524.
PMID: 34122910
The enzymes glucose oxidase (GOx), acetylcholine esterase (AchE) and urease that drive biocatalytic transformations to alter pH, are integrated into pH-responsive DNA-based hydrogels. A two-enzyme-loaded hydrogel composed of GOx/urease or...
10.
Lilienthal S, Luo G, Wang S, Yue L, Fischer A, Ehrlich A, et al.
J Am Chem Soc
. 2020 Dec;
142(51):21460-21468.
PMID: 33290051
Inspired by nature, where dynamic networks control the levels of gene expression and the activities of transcribed/translated proteins, we introduce nucleic acid-based constitutional dynamic networks (CDNs) as functional modules mimicking...