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Amirali H Talasaz

Explore the profile of Amirali H Talasaz including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Cann G, Gulzar Z, Cooper S, Li R, Luo S, Tat M, et al.
PLoS One . 2012 Nov; 7(11):e49144. PMID: 23145101
Circulating tumor cells (CTC) mediate metastatic spread of many solid tumors and enumeration of CTCs is currently used as a prognostic indicator of survival in metastatic prostate cancer patients. Some...
2.
Powell A, Talasaz A, Zhang H, Coram M, Reddy A, Deng G, et al.
PLoS One . 2012 May; 7(5):e33788. PMID: 22586443
Background: To improve cancer therapy, it is critical to target metastasizing cells. Circulating tumor cells (CTCs) are rare cells found in the blood of patients with solid tumors and may...
3.
Javanmard M, Talasaz A, Nemat-Gorgani M, Huber D, Pease F, Ronaghi M, et al.
IEEE Sens J . 2010 May; 9(8):883-891. PMID: 20467571
Traditionally, expensive and time consuming techniques such as mass spectrometry and Western Blotting have been used for characterization of protein-protein interactions. In this paper, we describe the design, fabrication, and...
4.
Javanmard M, Talasaz A, Nemat-Gorgani M, Pease F, Ronaghi M, Davis R
Biomicrofluidics . 2009 Aug; 1(4):44103. PMID: 19693402
Currently, microbiological techniques such as culture enrichment and various plating techniques are used for detection of pathogens. These expensive and time consuming methods can take several days. Described below is...
5.
Javanmard M, Talasaz A, Nemat-Gorgani M, Pease F, Ronaghi M, Davis R
Lab Chip . 2009 May; 9(10):1429-34. PMID: 19417910
Current methods used for analyzing biomarkers involve expensive and time consuming techniques like the Sandwich ELISA which require lengthy incubation times, high reagent costs, and bulky optical equipment. We have...
6.
Talasaz A, Powell A, Huber D, Berbee J, Roh K, Yu W, et al.
Proc Natl Acad Sci U S A . 2009 Feb; 106(10):3970-5. PMID: 19234122
The enumeration of rare circulating epithelial cells (CEpCs) in the peripheral blood of metastatic cancer patients has shown promise for improved cancer prognosis. Moving beyond enumeration, molecular analysis of CEpCs...
7.
Bigdeli S, Talasaz A, Stahl P, Persson H, Ronaghi M, Davis R, et al.
Biotechnol Bioeng . 2007 Dec; 100(1):19-27. PMID: 18078298
The present study reports on the retention of conformational flexibility of a model allosteric protein upon immobilization on self-assembled monolayers (SAMs) on gold. Organothiolated SAMs of different compositions were utilized...
8.
Talasaz A, Liu Y, Ronaghi M, Davis R
Conf Proc IEEE Eng Med Biol Soc . 2007 Oct; 2006:1830-3. PMID: 17946483
This paper presents the modeling of the electrical properties of bioactivated nanopores, customized nanopore devices with a biological macromolecule attached in the pore as the probe. These devices are capable...
9.
Talasaz A, Powell A, Stahl P, Ronaghi M, Jeffrey S, Mindrinos M, et al.
Conf Proc IEEE Eng Med Biol Soc . 2007 Oct; 2006:1838-41. PMID: 17945673
This paper presents a novel device which provides the opportunity to perform high-throughput biochemical assays on different individual cells. In particular, the proposed device is suited to screen the rare...
10.
Talasaz A, Nemat-Gorgani M, Liu Y, Stahl P, Dutton R, Ronaghi M, et al.
Proc Natl Acad Sci U S A . 2006 Sep; 103(40):14773-8. PMID: 17001006
We report on a rapid simulation method for predicting protein orientation on a surface based on electrostatic interactions. New methods for predicting protein immobilization are needed because of the increasing...