Amir Ali Ghaffari
Overview
Explore the profile of Amir Ali Ghaffari including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
376
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0
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Recent Articles
1.
Ertem F, Rivers C, Ghaffari A, Watson A, Tang G, Schwartz M, et al.
Inflamm Bowel Dis
. 2024 Jul;
31(2):461-466.
PMID: 38953641
Background: Almost half of patients with Crohn's disease (CD) require bowel surgeries in their lifetime. Due to the high risk of postoperative disease recurrence and high rate of previous antitumor...
2.
Aliyari S, Ghaffari A, Pernet O, Parvatiyar K, Wang Y, Gerami H, et al.
Acta Pharm Sin B
. 2022 Mar;
12(4):1624-1635.
PMID: 35251918
SARS-CoV-2 is an emerging viral pathogen and a major global public health challenge since December of 2019, with limited effective treatments throughout the pandemic. As part of the innate immune...
3.
Ding X, Krutzik P, Ghaffari A, Zhaozhi Y, Miranda Jr D, Cheng G, et al.
Antiviral Res
. 2019 Sep;
171:104598.
PMID: 31513822
As antiviral drug resistance develops and new viruses emerge there is a pressing need to develop strategies to rapidly develop antiviral therapeutics. Here we use phospho-specific flow cytometry to assess...
4.
Tian X, Xu F, Lung W, Meyerson C, Ghaffari A, Cheng G, et al.
PLoS One
. 2012 Sep;
7(9):e41879.
PMID: 22962579
Secondary bacterial pneumonias are a frequent complication of influenza and other respiratory viral infections, but the mechanisms underlying viral-induced susceptibility to bacterial infections are poorly understood. In particular, it is...
5.
Zhang Z, Kim T, Bao M, Facchinetti V, Jung S, Ghaffari A, et al.
Immunity
. 2011 Jun;
34(6):866-78.
PMID: 21703541
The innate immune system detects viral infection predominantly by sensing viral nucleic acids. We report the identification of a viral sensor, consisting of RNA helicases DDX1, DDX21, and DHX36, and...
6.
Iyer S, Ghaffari A, Cheng G
J Immunol
. 2010 Nov;
185(11):6599-607.
PMID: 21041726
IL-10 is a potent anti-inflammatory molecule that regulates excessive production of inflammatory cytokines during an infection or tissue damage. Dysregulation of IL-10 is associated with a number of autoimmune diseases,...