Ami Graham
Overview
Explore the profile of Ami Graham including associated specialties, affiliations and a list of published articles.
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10
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2364
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Recent Articles
1.
Christoffel D, Golden S, Heshmati M, Graham A, Birnbaum S, Neve R, et al.
Neuropsychopharmacology
. 2012 Jul;
37(12):2615-23.
PMID: 22781845
Inhibitor of κB kinase (IκK) has historically been studied in the context of immune response and inflammation, but recent evidence demonstrates that IκK activity is necessary and sufficient for regulation...
2.
Coque L, Mukherjee S, Cao J, Spencer S, Marvin M, Falcon E, et al.
Neuropsychopharmacology
. 2011 Mar;
36(7):1478-88.
PMID: 21430648
Lithium has been used extensively for mood stabilization, and it is particularly efficacious in the treatment of bipolar mania. Like other drugs used in the treatment of psychiatric diseases, it...
3.
Mukherjee S, Coque L, Cao J, Kumar J, Chakravarty S, Asaithamby A, et al.
Biol Psychiatry
. 2010 Jul;
68(6):503-11.
PMID: 20591414
Background: Circadian rhythm abnormalities are strongly associated with bipolar disorder; however the role of circadian genes in mood regulation is unclear. Previously, we reported that mice with a mutation in...
4.
Russo S, Wilkinson M, Mazei-Robison M, Dietz D, Maze I, Krishnan V, et al.
J Neurosci
. 2009 Mar;
29(11):3529-37.
PMID: 19295158
Although chronic cocaine-induced changes in dendritic spines on nucleus accumbens (NAc) neurons have been correlated with behavioral sensitization, the molecular pathways governing these structural changes, and their resulting behavioral effects,...
5.
LaPlant Q, Chakravarty S, Vialou V, Mukherjee S, Koo J, Kalahasti G, et al.
Biol Psychiatry
. 2009 Mar;
65(10):874-80.
PMID: 19251249
Background: The molecular mechanisms of stress-induced depressive behaviors have been characterized extensively in male rodents; however, much less is known about female subjects, despite the fact that human depression is...
6.
Graham D, Krishnan V, Larson E, Graham A, Edwards S, Bachtell R, et al.
Biol Psychiatry
. 2008 Nov;
65(8):696-701.
PMID: 18990365
Background: Previous studies found that brain-derived neurotrophic factor (BDNF) derived from nucleus accumbens (NAc) neurons can mediate persistent behavioral changes that contribute to cocaine addiction. Methods: To further investigate BDNF...
7.
Krishnan V, Graham A, Mazei-Robison M, Lagace D, Kim K, Birnbaum S, et al.
Biol Psychiatry
. 2008 May;
64(4):336-43.
PMID: 18468583
Background: Adenylyl cyclases (ACs) represent a diverse family of enzymes responsible for the generation of cyclic adenosine monophosphate (cAMP), a key intracellular second messenger. The Ca(2+)/calmodulin-stimulated AC1 and AC8 isoforms...
8.
Renthal W, Maze I, Krishnan V, Covington 3rd H, Xiao G, Kumar A, et al.
Neuron
. 2007 Nov;
56(3):517-29.
PMID: 17988634
Previous work has identified alterations in histone acetylation in animal models of drug addiction and depression. However, the mechanisms which integrate drugs and stress with changes in chromatin structure remain...
9.
Krishnan V, Han M, Graham D, Berton O, Renthal W, Russo S, et al.
Cell
. 2007 Oct;
131(2):391-404.
PMID: 17956738
While stressful life events are an important cause of psychopathology, most individuals exposed to adversity maintain normal psychological functioning. The molecular mechanisms underlying such resilience are poorly understood. Here, we...
10.
Roybal K, Theobold D, Graham A, Dinieri J, Russo S, Krishnan V, et al.
Proc Natl Acad Sci U S A
. 2007 Mar;
104(15):6406-11.
PMID: 17379666
Circadian rhythms and the genes that make up the molecular clock have long been implicated in bipolar disorder. Genetic evidence in bipolar patients suggests that the central transcriptional activator of...