Amer E Alkhalifa
Overview
Explore the profile of Amer E Alkhalifa including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
138
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Recent Articles
1.
Ayoub N, Al-Taani G, Alkhalifa A, Ibrahim D, Shatnawi A
Breast J
. 2025 Jan;
2024:2582341.
PMID: 39742369
Purpose: Breast cancer is a heterogeneous disease. Exploring new prognostic and therapeutic targets in patients with breast cancer is essential. This study investigated the expression of MET, ESR1, and ESR2...
2.
Al Rihani S, Elfakhri K, Ebrahim H, Al-Ghraiybah N, Alkhalifa A, El Sayed K, et al.
ACS Chem Neurosci
. 2024 Aug;
15(17):3152-3167.
PMID: 39145537
Preclinical and clinical studies have indicated that compromised blood-brain barrier (BBB) function contributes to Alzheimer's disease (AD) pathology. BBB breakdown ranged from mild disruption of tight junctions (TJs) with increased...
3.
Alkhalifa A, Al-Ghraiybah N, Kaddoumi A
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339193
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by several pathological hallmarks, including the deposition of amyloid-β (Aβ) plaques, neurofibrillary tangles, blood-brain barrier (BBB) dysfunction, increased oxidative...
4.
Alkhalifa A, Al-Ghraiybah N, Odum J, Shunnarah J, Austin N, Kaddoumi A
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003477
The blood-brain barrier (BBB) is a unique and selective feature of the central nervous system's vasculature. BBB dysfunction has been observed as an early sign of Alzheimer's Disease (AD) before...
5.
Abdallah I, Al-Shami K, Alkhalifa A, Al-Ghraiybah N, Guillaume C, Kaddoumi A
Molecules
. 2023 Feb;
28(3).
PMID: 36770920
Alzheimer's disease (AD) is characterized by several pathological hallmarks, including the deposition of amyloid-β (Aβ) plaques, neurofibrillary tangles, blood-brain barrier (BBB) dysfunction, and neuroinflammation. Growing evidence support the neuroprotective effects...
6.
Al-Ghraiybah N, Wang J, Alkhalifa A, Roberts A, Raj R, Yang E, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142483
Alzheimer's disease (AD) is a progressive neurodegenerative disorder; it is the most common cause of dementia and has no treatment. It is characterized by two pathological hallmarks, the extracellular deposits...
7.
Shatnawi A, Ayoub N, Alkhalifa A, Ibrahim D
Breast Cancer (Auckl)
. 2022 Apr;
16:11782234221086713.
PMID: 35359609
Purpose: It has been suggested that dysregulation of transcription factors expression or activity plays significant roles in breast cancer (BC) severity and poor prognosis. Therefore, our study aims to thoroughly...
8.
Ayoub N, Jaradat S, Al-Shami K, Alkhalifa A
Front Pharmacol
. 2022 Mar;
13:838133.
PMID: 35281942
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous molecular pathways are known to drive angiogenic switch in cancer cells promoting the growth of new...
9.
Ayoub N, Ibrahim D, Alkhalifa A
Med Oncol
. 2021 Oct;
38(12):143.
PMID: 34665336
Targeted therapy is a hallmark of cancer treatment that has changed the landscape of cancer management and enabled a personalized treatment approach. Nevertheless, the development of cancer resistance is a...
10.
Ayoub N, Alkhalifa A, Ibrahim D, Alhusban A
Med Oncol
. 2021 Jan;
38(1):8.
PMID: 33449292
Hormone-dependent breast cancer is the most abundant molecular subtype of the disease. Despite the availability of endocrine treatments, the use of these drugs is limited by their serious adverse reactions...