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Amelie Malapert

Explore the profile of Amelie Malapert including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 147
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Recent Articles
1.
Vacheron C, Bitker L, Thiolliere F, Subtil F, Abraham P, Collange V, et al.
Turk J Anaesthesiol Reanim . 2022 Jul; 50(Supp1):S57-S61. PMID: 35775799
Objective: Admission in the intensive care unit of the old patient with coronavirus disease 19 raises an ethical question concerning the scarce resources and their short-term mortality. Methods: Patients aged...
2.
Falandry C, Bitker L, Abraham P, Subtil F, Collange V, Balanca B, et al.
Aging Dis . 2022 Apr; 13(2):614-623. PMID: 35371615
The SARS-COV2 pandemic induces tensions on health systems and ethical dilemmas. Practitioners need help tools to define patients not candidate for ICU admission. A multicentre observational study was performed to...
3.
Falandry C, Malapert A, Roche M, Subtil F, Berthiller J, Boin C, et al.
BMJ Open . 2021 Jul; 11(7):e044449. PMID: 34230013
Introduction: With the spread of COVID-19 epidemic, health plans must be adapted continuously. There is an urgent need to define the best care courses of patients with COVID-19, especially in...
4.
Roche M, Ravot C, Malapert A, Paget-Bailly S, Garandeau C, Pitiot V, et al.
BMJ Open . 2021 Apr; 11(4):e042960. PMID: 33811052
Background: Ageing is associated with an increased prevalence of comorbidities and sarcopenia as well as a decline of functional reserve of multiple organ systems, which may lead, in the context...
5.
Rivosecchi J, Larochelle M, Teste C, Grenier F, Malapert A, Ricci E, et al.
EMBO J . 2019 Jul; 38(16):e101955. PMID: 31294478
R-loop disassembly by the human helicase Senataxin contributes to genome integrity and to proper transcription termination at a subset of RNA polymerase II genes. Whether Senataxin also contributes to transcription...
6.
Carrasco-Salas Y, Malapert A, Sulthana S, Molcrette B, Chazot-Franguiadakis L, Bernard P, et al.
Nucleic Acids Res . 2019 May; 47(13):6783-6795. PMID: 31066439
Three-stranded R-loop structures have been associated with genomic instability phenotypes. What underlies their wide-ranging effects on genome stability remains poorly understood. Here we combined biochemical and atomic force microscopy approaches...
7.
Hartono S, Malapert A, Legros P, Bernard P, Chedin F, Vanoosthuyse V
J Mol Biol . 2018 Jan; 430(3):272-284. PMID: 29289567
R-loops, which result from the formation of stable DNA:RNA hybrids, can both threaten genome integrity and act as physiological regulators of gene expression and chromatin patterning. To characterize R-loops in...
8.
Legros P, Malapert A, Niinuma S, Bernard P, Vanoosthuyse V
PLoS Genet . 2014 Nov; 10(11):e1004794. PMID: 25392932
Condensin-mediated chromosome condensation is essential for genome stability upon cell division. Genetic studies have indicated that the association of condensin with chromatin is intimately linked to gene transcription, but what...