Amelia N Chang
Overview
Explore the profile of Amelia N Chang including associated specialties, affiliations and a list of published articles.
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6
Citations
311
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Recent Articles
1.
Wang Y, Chiola S, Yang G, Russell C, Armstrong C, Wu Y, et al.
Nat Commun
. 2022 Oct;
13(1):5688.
PMID: 36202854
Human telencephalon is an evolutionarily advanced brain structure associated with many uniquely human behaviors and disorders. However, cell lineages and molecular pathways implicated in human telencephalic development remain largely unknown....
2.
Cheng Y, Snavely A, Barrett L, Zhang X, Herman C, Frost D, et al.
Cell Rep
. 2021 Sep;
36(10):109666.
PMID: 34496254
Although axonal damage induces rapid changes in gene expression in primary sensory neurons, it remains unclear how this process is initiated. The transcription factor ATF3, one of the earliest genes...
3.
Dai H, Liang Z, Chang A, Chapdelaine-Williams A, Alvarado B, Pollen A, et al.
Nat Protoc
. 2020 Aug;
15(10):3154-3181.
PMID: 32778838
We provide a protocol for generating forebrain structures in vivo from mouse embryonic stem cells (ESCs) via neural blastocyst complementation (NBC). We developed this protocol for studies of development and...
4.
Chang A, Liang Z, Dai H, Chapdelaine-Williams A, Andrews N, Bronson R, et al.
Nature
. 2018 Oct;
563(7729):126-130.
PMID: 30305734
Genetically modified mice are commonly generated by the microinjection of pluripotent embryonic stem (ES) cells into wild-type host blastocysts, producing chimeric progeny that require breeding for germline transmission and homozygosity...
5.
Schwer B, Wei P, Chang A, Kao J, Du Z, Meyers R, et al.
Proc Natl Acad Sci U S A
. 2016 Feb;
113(8):2258-63.
PMID: 26873106
High-throughput, genome-wide translocation sequencing (HTGTS) studies of activated B cells have revealed that DNA double-strand breaks (DSBs) capable of translocating to defined bait DSBs are enriched around the transcription start...
6.
Wei P, Chang A, Kao J, Du Z, Meyers R, Alt F, et al.
Cell
. 2016 Feb;
164(4):644-55.
PMID: 26871630
Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for neural development, and brain cells frequently contain somatic genomic variations that might involve DSB intermediates. We now...