Amelia Marutle
Overview
Explore the profile of Amelia Marutle including associated specialties, affiliations and a list of published articles.
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23
Citations
752
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Recent Articles
1.
Ni R, Rojdner J, Voytenko L, Dyrks T, Thiele A, Marutle A, et al.
J Alzheimers Dis
. 2021 Mar;
80(4):1723-1737.
PMID: 33749648
Background: Emerging evidence indicates a central role of gliosis in Alzheimer's disease (AD) pathophysiology. However, the regional distribution and interaction of astrogliosis and microgliosis in association with amyloid-β (Aβ) still...
2.
Lilja A, Malmsten L, Rojdner J, Voytenko L, Verkhratsky A, Ogren S, et al.
Neural Plast
. 2015 Aug;
2015:370432.
PMID: 26257960
Stimulating regeneration in the brain has the potential to rescue neuronal networks and counteract progressive pathological changes in Alzheimer's disease (AD). This study investigated whether drugs with different mechanisms of...
3.
Lemoine L, Saint-Aubert L, Marutle A, Antoni G, Eriksson J, Ghetti B, et al.
Acta Neuropathol Commun
. 2015 Jul;
3:40.
PMID: 26134112
Introduction: The accumulation of neurofibrillary tangles, composed of aggregated hyperphosphorylated tau protein, starts spreading early in specific regions in the course of Alzheimer's disease (AD), correlating with the progression of...
4.
Rodriguez-Vieitez E, Ni R, Gulyas B, Toth M, Haggkvist J, Halldin C, et al.
Eur J Nucl Med Mol Imaging
. 2015 Apr;
42(7):1119-32.
PMID: 25893384
Purpose: Pathological studies suggest that neuroinflammation is exacerbated by increased beta-amyloid (Aβ) levels in the brain early in Alzheimer's disease (AD). The time course and relationships between astrocytosis and Aβ...
5.
Verkhratsky A, Marutle A, Rodriguez-Arellano J, Nordberg A
Neuroscientist
. 2014 Aug;
21(5):552-568.
PMID: 25125026
Neuroglia are represented by several population of cells heterogeneous in structure and function that provide for the homeostasis of the brain and the spinal cord. Neuroglial cells are also central...
6.
Malmsten L, Vijayaraghavan S, Hovatta O, Marutle A, Darreh-Shori T
J Cell Mol Med
. 2014 Aug;
18(9):1874-88.
PMID: 25109373
Adult neurogenesis is impaired by inflammatory processes, which are linked to altered cholinergic signalling and cognitive decline in Alzheimer's disease. In this study, we investigated how amyloid beta (Aβ)-evoked inflammatory...
7.
Marutle A, Gillberg P, Bergfors A, Yu W, Ni R, Nennesmo I, et al.
J Neuroinflammation
. 2013 Jul;
10:90.
PMID: 23880036
Background: The pathological features in Alzheimer's disease (AD) brain include the accumulation and deposition of β-amyloid (Aβ), activation of astrocytes and microglia and disruption of cholinergic neurotransmission. Since the topographical...
8.
Ni R, Gillberg P, Bergfors A, Marutle A, Nordberg A
Brain
. 2013 Jun;
136(Pt 7):2217-27.
PMID: 23757761
Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission tomography has improved our understanding of the time course of amyloid-β pathology in Alzheimer's disease. The most...
9.
Lilja A, Rojdner J, Mustafiz T, Thome C, Storelli E, Gonzalez D, et al.
PLoS One
. 2013 Apr;
8(3):e58752.
PMID: 23554921
The objective of this study was to investigate the effects of modulating brain amyloid-β (Aβ) levels at different stages of amyloid pathology on synaptic function, inflammatory cell changes and hippocampal...
10.
Lilja A, Luo Y, Yu Q, Rojdner J, Li Y, Marini A, et al.
PLoS One
. 2013 Feb;
8(1):e54887.
PMID: 23382994
Neuronal dysfunction and demise together with a reduction in neurogenesis are cardinal features of Alzheimer's disease (AD) induced by a combination of oxidative stress, toxic amyloid-β peptide (Aβ) and a...