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Amelia Bartholomew

Explore the profile of Amelia Bartholomew including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Black E, Marini L, Vaidya A, Berman D, Willman M, Salomon D, et al.
Proc IEEE Int Conf Escience . 2015 Jun; 1:83-91. PMID: 26075290
A novel application of Hidden Markov Models is used to help research intended to test the immunuregulatory effects of mesenchymal stem cells in a cynomolgus monkey model of islet transplantation....
12.
Strojny C, Boyle M, Bartholomew A, Sundivakkam P, Alapati S
J Endod . 2015 Jun; 41(8):1259-64. PMID: 26051078
Introduction: Chronic inflammation disrupts dental pulp regeneration by disintegrating the recruitment process of progenitors for repair. Bone marrow-derived mesenchymal stem cells (BM-MSCs) share the common features with dental pulp stem...
13.
Boyle M, Chun C, Strojny C, Narayanan R, Bartholomew A, Sundivakkam P, et al.
PLoS One . 2014 Nov; 9(11):e113419. PMID: 25427002
Dental-pulp tissue is often exposed to inflammatory injury. Sequested growth factors or angiogenic signaling proteins that are released following inflammatory injury play a pivotal role in the formation of reparative...
14.
Ennis W, Sui A, Bartholomew A
Adv Wound Care (New Rochelle) . 2014 Mar; 2(7):369-378. PMID: 24587974
Significance: The number of patients with nonhealing wounds has rapidly accelerated over the past 10 years in both the United States and worldwide. Some causative factors at the macro level...
15.
Qi M, Wang Y, Formo K, Marchese E, Wang S, McGarrigle J, et al.
Pancreas . 2014 Feb; 43(2):226-35. PMID: 24518500
Objectives: The present study describes a simple and cost-effective islet isolation procedure. Using this method, allogeneic islets reverse diabetes in cynomolgus monkeys. Methods: Pancreatic tissue from 11 cynomolgus monkeys were...
16.
Demars M, Bartholomew A, Strakova Z, Lazarov O
Stem Cell Res Ther . 2011 Sep; 2(4):36. PMID: 21878106
Introduction: Soluble amyloid precursor protein α (sAPPα) is a proteolyte of APP cleavage by α-secretase. The significance of the cleavage and the physiological role of sAPPα are unknown. A crystal...
17.
Hoogduijn M, Popp F, Grohnert A, Crop M, van Rhijn M, Rowshani A, et al.
Transplantation . 2010 Jul; 90(2):124-6. PMID: 20606604
There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number...
18.
Dahlke M, Hoogduijn M, Eggenhofer E, Popp F, Renner P, Slowik P, et al.
Transplantation . 2009 Sep; 88(5):614-9. PMID: 19741455
The following position paper summarizes the recommendations for early clinical trials and ongoing basic research in the field of mesenchymal stem cell-induced solid organ graft acceptance--agreed upon on the first...
19.
Bartholomew A, Polchert D, Szilagyi E, Douglas G, Kenyon N
Transplantation . 2009 May; 87(9 Suppl):S55-7. PMID: 19424008
Mesenchymal stem cells directly suppress ongoing immune responses. Through production of toleragenic cytokines, inhibition of lymphocyte proliferation, delivery of reparative and protective signals after reperfusion injury, and facilitation of hematopoietic...
20.
Polchert D, Sobinsky J, Douglas G, Kidd M, Moadsiri A, Reina E, et al.
Eur J Immunol . 2008 May; 38(6):1745-55. PMID: 18493986
Graft versus host disease (GVHD), mediated by donor T cells, is a significant source of morbidity and mortality following allogeneic stem cell transplantation. Mesenchymal stem cells (MSC) can successfully treat...